Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HL037260-17
Application #
6629121
Study Section
Special Emphasis Panel (NSS)
Program Officer
Pearson, Gail D
Project Start
2000-02-15
Project End
2005-01-31
Budget Start
2003-02-01
Budget End
2004-01-31
Support Year
17
Fiscal Year
2003
Total Cost
$250,794
Indirect Cost

  Institution

Name
National Jewish Health
Department
Type
DUNS #
076443019
City
Denver
State
CO
Country
United States
Zip Code
80206

  Publications

Zhang, Yong; Leung, Donald Y M; Goleva, Elena (2014) Anti-inflammatory and corticosteroid-enhancing actions of vitamin D in monocytes of patients with steroid-resistant and those with steroid-sensitive asthma. J Allergy Clin Immunol 133:1744-52.e1
Goleva, Elena; Jackson, Leisa P; Harris, J Kirk et al. (2013) The effects of airway microbiome on corticosteroid responsiveness in asthma. Am J Respir Crit Care Med 188:1193-201
Zhang, Yong; Leung, Donald Y M; Goleva, Elena (2013) Vitamin D enhances glucocorticoid action in human monocytes: involvement of granulocyte-macrophage colony-stimulating factor and mediator complex subunit 14. J Biol Chem 288:14544-53
Goleva, Elena; Searing, Daniel A; Jackson, Leisa P et al. (2012) Steroid requirements and immune associations with vitamin D are stronger in children than adults with asthma. J Allergy Clin Immunol 129:1243-51
Goleva, Elena; Jackson, Leisa P; Gleason, Melanie et al. (2012) Usefulness of PBMCs to predict clinical response to corticosteroids in asthmatic patients. J Allergy Clin Immunol 129:687-693.e1
Zhang, Yong; Leung, Donald Y M; Richers, Brittany N et al. (2012) Vitamin D inhibits monocyte/macrophage proinflammatory cytokine production by targeting MAPK phosphatase-1. J Immunol 188:2127-35
Li, Ling-Bo; Leung, Donald Y M; Martin, Richard J et al. (2010) Inhibition of histone deacetylase 2 expression by elevated glucocorticoid receptor beta in steroid-resistant asthma. Am J Respir Crit Care Med 182:877-83
Searing, Daniel A; Zhang, Yong; Murphy, James R et al. (2010) Decreased serum vitamin D levels in children with asthma are associated with increased corticosteroid use. J Allergy Clin Immunol 125:995-1000
Goleva, Elena; Li, Ling-Bo; Leung, Donald Y M (2009) IFN-gamma reverses IL-2- and IL-4-mediated T-cell steroid resistance. Am J Respir Cell Mol Biol 40:223-30
Goleva, Elena; Hauk, Pia J; Hall, Clifton F et al. (2008) Corticosteroid-resistant asthma is associated with classical antimicrobial activation of airway macrophages. J Allergy Clin Immunol 122:550-9.e3

Showing the most recent 10 out of 124 publications