Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
2R37HL038859-06A1
Application #
3486197
Study Section
Human Embryology and Development Subcommittee 1 (HED)
Project Start
1987-07-01
Project End
1998-03-31
Budget Start
1993-04-01
Budget End
1994-03-31
Support Year
6
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
Besnard, Valérie; Matsuzaki, Yohei; Clark, Jean et al. (2010) Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice. Am J Physiol Lung Cell Mol Physiol 298:L646-59
Cardoso, Wellington V; Whitsett, Jeffrey A (2008) Resident cellular components of the lung: developmental aspects. Proc Am Thorac Soc 5:767-71
Ikegami, Machiko; Falcone, Angelica; Whitsett, Jeffrey A (2008) STAT-3 regulates surfactant phospholipid homeostasis in normal lung and during endotoxin-mediated lung injury. J Appl Physiol 104:1753-60
Matsuzaki, Yohei; Besnard, Valerie; Clark, Jean C et al. (2008) STAT3 regulates ABCA3 expression and influences lamellar body formation in alveolar type II cells. Am J Respir Cell Mol Biol 38:551-8
Park, Kwon-Sik; Korfhagen, Thomas R; Bruno, Michael D et al. (2007) SPDEF regulates goblet cell hyperplasia in the airway epithelium. J Clin Invest 117:978-88
Berclaz, Pierre-Yves; Carey, Brenna; Fillipi, Marie-Dominique et al. (2007) GM-CSF regulates a PU.1-dependent transcriptional program determining the pulmonary response to LPS. Am J Respir Cell Mol Biol 36:114-21
Maeda, Yutaka; Dave, Vrushank; Whitsett, Jeffrey A (2007) Transcriptional control of lung morphogenesis. Physiol Rev 87:219-44
Stahlman, Mildred T; Besnard, Valerie; Wert, Susan E et al. (2007) Expression of ABCA3 in developing lung and other tissues. J Histochem Cytochem 55:71-83
Bry, Kristina; Whitsett, Jeffrey A; Lappalainen, Urpo (2007) IL-1beta disrupts postnatal lung morphogenesis in the mouse. Am J Respir Cell Mol Biol 36:32-42
Dave, Vrushank; Childs, Tawanna; Xu, Yan et al. (2006) Calcineurin/Nfat signaling is required for perinatal lung maturation and function. J Clin Invest 116:2597-609

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