Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HL039753-09
Application #
2219355
Study Section
Special Emphasis Panel (NSS)
Project Start
1988-02-01
Project End
1998-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Kuter, D J; Rosenberg, R D (1995) The reciprocal relationship of thrombopoietin (c-Mpl ligand) to changes in the platelet mass during busulfan-induced thrombocytopenia in the rabbit. Blood 85:2720-30
Ravid, K; Kuter, D J; Rosenberg, R D (1995) rmIL-6 stimulates the transcriptional activity of the rat PF4 gene. Exp Hematol 23:397-401
Aird, W C; Parvin, J D; Sharp, P A et al. (1994) The interaction of GATA-binding proteins and basal transcription factors with GATA box-containing core promoters. A model of tissue-specific gene expression. J Biol Chem 269:883-9
Kuter, D J; Rosenberg, R D (1994) Appearance of a megakaryocyte growth-promoting activity, megapoietin, during acute thrombocytopenia in the rabbit. Blood 84:1464-72
Kuter, D J; Beeler, D L; Rosenberg, R D (1994) The purification of megapoietin: a physiological regulator of megakaryocyte growth and platelet production. Proc Natl Acad Sci U S A 91:11104-8
Ravid, K; Kuter, D J; Beeler, D L et al. (1993) Selection of an HEL-derived cell line expressing high levels of platelet factor 4. Blood 81:2885-90
Ravid, K; Li, Y C; Rayburn, H B et al. (1993) Targeted expression of a conditional oncogene in hematopoietic cells of transgenic mice. J Cell Biol 123:1545-53
Plutzky, J; Neel, B G; Rosenberg, R D (1992) Isolation of a src homology 2-containing tyrosine phosphatase. Proc Natl Acad Sci U S A 89:1123-7
Kuter, D J; Gminski, D M; Rosenberg, R D (1992) Transforming growth factor beta inhibits megakaryocyte growth and endomitosis. Blood 79:619-26
Kuter, D J; Gminski, D; Rosenberg, R D (1992) Botrocetin agglutination of rat megakaryocytes: a rapid method for megakaryocyte isolation. Exp Hematol 20:1085-9

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