Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
2R37HL042630-10
Application #
2615458
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1989-04-01
Project End
2003-03-31
Budget Start
1998-04-01
Budget End
1999-03-31
Support Year
10
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Pathology
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Kayashima, Yukako; Makhanova, Natalia; Maeda, Nobuyo (2017) DBA/2J Haplotype on Distal Chromosome 2 Reduces Mertk Expression, Restricts Efferocytosis, and Increases Susceptibility to Atherosclerosis. Arterioscler Thromb Vasc Biol 37:e82-e91
Liu, Ya-Hui; Tsai, Yau-Sheng; Lin, Shih-Chieh et al. (2016) Quantitative PPAR? expression affects the balance between tolerance and immunity. Sci Rep 6:26646
Tai, Haw-Chih; Tsai, Pei-Jane; Chen, Ju-Yi et al. (2016) Peroxisome Proliferator-Activated Receptor ? Level Contributes to Structural Integrity and Component Production of Elastic Fibers in the Aorta. Hypertension 67:1298-308
Kayashima, Yukako; Makhanova, Natalia A; Matsuki, Kota et al. (2015) Identification of aortic arch-specific quantitative trait loci for atherosclerosis by an intercross of DBA/2J and 129S6 apolipoprotein E-deficient mice. PLoS One 10:e0117478
Hiller, Sylvia; DeKroon, Robert; Xu, Longquan et al. (2014) ?-Lipoic acid protects mitochondrial enzymes and attenuates lipopolysaccharide-induced hypothermia in mice. Free Radic Biol Med 71:362-7
Kayashima, Yukako; Tomita, Hirofumi; Zhilicheva, Svetlana et al. (2014) Quantitative trait loci affecting atherosclerosis at the aortic root identified in an intercross between DBA2J and 129S6 apolipoprotein E-null mice. PLoS One 9:e88274
Wölkart, G; Beretta, M; Wenzl, M V et al. (2013) Tolerance to nitroglycerin through proteasomal down-regulation of aldehyde dehydrogenase-2 in a genetic mouse model of ascorbate deficiency. Br J Pharmacol 168:1868-77
Wait, John M S; Tomita, Hirofumi; Burk, Laurel M et al. (2013) Detection of aortic arch calcification in apolipoprotein E-null mice using carbon nanotube-based micro-CT system. J Am Heart Assoc 2:e003358
Johnson, Lance A; Kim, Hyung-Suk; Knudson, Melissa J et al. (2013) Diabetic atherosclerosis in APOE*4 mice: synergy between lipoprotein metabolism and vascular inflammation. J Lipid Res 54:386-96
Fox, Raymond G; Magness, Scott; Kujoth, Gregory C et al. (2012) Mitochondrial DNA polymerase editing mutation, PolgD257A, disturbs stem-progenitor cell cycling in the small intestine and restricts excess fat absorption. Am J Physiol Gastrointest Liver Physiol 302:G914-24

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