Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37HL043413-11
Application #
2898675
Study Section
Special Emphasis Panel (NSS)
Project Start
1989-07-01
Project End
2005-05-31
Budget Start
2000-06-01
Budget End
2001-05-31
Support Year
11
Fiscal Year
2000
Total Cost
$274,710
Indirect Cost
Name
University of Pennsylvania
Department
Physiology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Lahiri, S; Roy, A; Baby, S M et al. (2009) Carotid body sensory discharge and glomus cell HIF-1 alpha are regulated by a common oxygen sensor. Adv Exp Med Biol 645:87-94
Lahiri, S; Mitchell, C H; Reigada, D et al. (2007) Purines, the carotid body and respiration. Respir Physiol Neurobiol 157:123-9
Roy, Arijit; Baby, Santhosh M; Wilson, David F et al. (2007) Rat carotid body chemosensory discharge and glomus cell HIF-1 alpha expression in vitro: regulation by a common oxygen sensor. Am J Physiol Regul Integr Comp Physiol 293:R829-36
Lahiri, S; Roy, A; Baby, S M et al. (2006) Oxygen sensing in the body. Prog Biophys Mol Biol 91:249-86
Wilson, David F; Roy, Arijit; Lahiri, Sukhamay (2005) Immediate and long-term responses of the carotid body to high altitude. High Alt Med Biol 6:97-111
Baby, Santhosh M; Roy, Arijit; Lahiri, Sukhamay (2005) Role of mitochondria in the regulation of hypoxia-inducible factor-1alpha in the rat carotid body glomus cells. Histochem Cell Biol 124:69-76
Wilson, David F (2004) Identifying oxygen sensors by their photochemical action spectra. Methods Enzymol 381:690-704
Roy, Arijit; Volgin, Denys V; Baby, Santhosh M et al. (2004) Activation of HIF-1alpha mRNA by hypoxia and iron chelator in isolated rat carotid body. Neurosci Lett 363:229-32
Lahiri, Sukhamay; Roy, Arijit; Li, Jinquing et al. (2003) Ca2+ responses to hypoxia are mediated by IP3-R on Ca2+ store depletion. Adv Exp Med Biol 536:25-32
Di Giulio, C; Huang, W; Waters, V et al. (2003) Atrial natriuretic peptide stimulates cat carotid body chemoreceptors in vivo. Comp Biochem Physiol A Mol Integr Physiol 134:27-31

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