Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HL048509-05
Application #
2224564
Study Section
Cardiovascular and Pulmonary Research A Study Section (CVA)
Project Start
1992-09-30
Project End
1997-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of California Los Angeles
Department
Physiology
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095

  Publications

Groenke, Sabine; Larson, Eric D; Alber, Sarah et al. (2013) Complete atrial-specific knockout of sodium-calcium exchange eliminates sinoatrial node pacemaker activity. PLoS One 8:e81633
Bai, Yan; Morgan, Eric E; Giovannucci, David R et al. (2013) Different roles of the cardiac Na+/Ca2+-exchanger in ouabain-induced inotropy, cell signaling, and hypertrophy. Am J Physiol Heart Circ Physiol 304:H427-35
Jordan, Maria C; Henderson, Scott A; Han, Tieyan et al. (2010) Myocardial function with reduced expression of the sodium-calcium exchanger. J Card Fail 16:786-96
Larbig, Robert; Torres, Natalia; Bridge, John H B et al. (2010) Activation of reverse Na+-Ca2+ exchange by the Na+ current augments the cardiac Ca2+ transient: evidence from NCX knockout mice. J Physiol 588:3267-76
Blaustein, Mordecai P; Zhang, Jin; Chen, Ling et al. (2009) The pump, the exchanger, and endogenous ouabain: signaling mechanisms that link salt retention to hypertension. Hypertension 53:291-8
Goldhaber, Joshua I; Henderson, Scott A; Reuter, Hannes et al. (2005) Effects of Na+-Ca2+ exchange expression on excitation-contraction coupling in genetically modified mice. Ann N Y Acad Sci 1047:122-6
Li, Z; Matsuoka, S; Hryshko, L V et al. (1994) Cloning of the NCX2 isoform of the plasma membrane Na(+)-Ca2+ exchanger. J Biol Chem 269:17434-9
Tsuruya, Y; Bersohn, M M; Li, Z et al. (1994) Molecular cloning and functional expression of the guinea pig cardiac Na(+)-Ca2+ exchanger. Biochim Biophys Acta 1196:97-9