Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HL049042-12
Application #
6683253
Study Section
Special Emphasis Panel (NSS)
Program Officer
Thomas, John
Project Start
1992-09-01
Project End
2007-08-31
Budget Start
2003-09-01
Budget End
2004-08-31
Support Year
12
Fiscal Year
2003
Total Cost
$408,393
Indirect Cost
Name
Sierra Biomedical Research Corporation
Department
Type
DUNS #
783285752
City
Reno
State
NV
Country
United States
Zip Code
89502
Goodrich, A Daisy; Ersek, Adel; Varain, Nicole M et al. (2010) In vivo generation of beta-cell-like cells from CD34(+) cells differentiated from human embryonic stem cells. Exp Hematol 38:516-525.e4
Ersek, Adel; Pixley, John S; Goodrich, A Daisy et al. (2010) Persistent circulating human insulin in sheep transplanted in utero with human mesenchymal stem cells. Exp Hematol 38:311-20
Skopal-Chase, Jessica L; Pixley, John S; Torabi, Alireza et al. (2009) Immune ontogeny and engraftment receptivity in the sheep fetus. Fetal Diagn Ther 25:102-10
Porada, Christopher D; Harrison-Findik, Duygu D; Sanada, Chad et al. (2008) Development and characterization of a novel CD34 monoclonal antibody that identifies sheep hematopoietic stem/progenitor cells. Exp Hematol 36:1739-49
Porada, Christopher D; Zanjani, Esmail D; Almeida-Porad, Graca (2006) Adult mesenchymal stem cells: a pluripotent population with multiple applications. Curr Stem Cell Res Ther 1:365-9
Narayan, A Daisy; Chase, Jessica L; Lewis, Rachel L et al. (2006) Human embryonic stem cell-derived hematopoietic cells are capable of engrafting primary as well as secondary fetal sheep recipients. Blood 107:2180-3
Lucas, M Lee; Seidel, Nancy E; Porada, Christopher D et al. (2005) Improved transduction of human sheep repopulating cells by retrovirus vectors pseudotyped with feline leukemia virus type C or RD114 envelopes. Blood 106:51-8
Porada, Christopher D; Park, Paul J; Tellez, Joe et al. (2005) Male germ-line cells are at risk following direct-injection retroviral-mediated gene transfer in utero. Mol Ther 12:754-62
Porada, Christopher D; Park, Paul J; Almeida-Porada, Graca et al. (2005) Gestational age of recipient determines pattern and level of transgene expression following in utero retroviral gene transfer. Mol Ther 11:284-93
Airey, Judith A; Almeida-Porada, Graca; Colletti, Evan J et al. (2004) Human mesenchymal stem cells form Purkinje fibers in fetal sheep heart. Circulation 109:1401-7

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