Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37MH038623-17
Application #
2244644
Study Section
Special Emphasis Panel (NSS)
Project Start
1983-04-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Albert Einstein College of Medicine
Department
Pathology
Type
Schools of Medicine
DUNS #
009095365
City
Bronx
State
NY
Country
United States
Zip Code
10461
Weinger, Jason G; Davies, Peter; Acker, Christopher M et al. (2012) Mice devoid of Tau have increased susceptibility to neuronal damage in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis. J Neuropathol Exp Neurol 71:422-33
Boutajangout, Allal; Ingadottir, Johanna; Davies, Peter et al. (2011) Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain. J Neurochem 118:658-67
Davies, Peter; Koppel, Jeremy (2009) Mechanism-based treatments for Alzheimer's disease. Dialogues Clin Neurosci 11:159-69
Herskovits, A Z; Davies, P (2006) The regulation of tau phosphorylation by PCTAIRE 3: implications for the pathogenesis of Alzheimer's disease. Neurobiol Dis 23:398-408
Marambaud, Philippe; Zhao, Haitian; Davies, Peter (2005) Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides. J Biol Chem 280:37377-82
Andorfer, Cathy; Kress, Yvonne; Espinoza, Marisol et al. (2003) Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms. J Neurochem 86:582-90
Ramakrishnan, Pankajavalli; Dickson, Dennis W; Davies, Peter (2003) Pin1 colocalization with phosphorylated tau in Alzheimer's disease and other tauopathies. Neurobiol Dis 14:251-64
Bu, Bitao; Li, Jin; Davies, Peter et al. (2002) Deregulation of cdk5, hyperphosphorylation, and cytoskeletal pathology in the Niemann-Pick type C murine model. J Neurosci 22:6515-25
Zamora-Leon, S P; Lee, G; Davies, P et al. (2001) Binding of Fyn to MAP-2c through an SH3 binding domain. Regulation of the interaction by ERK2. J Biol Chem 276:39950-8
Andorfer, C A; Davies, P (2000) PKA phosphorylations on tau: developmental studies in the mouse. Dev Neurosci 22:303-9

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