The objective of the proposed work is to determine whether a novel proprietory device designed to detect active Lyme disease spirochetal infection can be exploited commercially. This device is intended to perfuse the skin of a patient and automatically deliver the sample into a vessel containing culture medium. In Phase I of this project, various prototype models of the proposed perfusion device will be constructed and tested. The diagnostic sensitivity of the procedure will be evaluated in mice, rabbits and pigs. During Phase II, the device will be evaluated using human patients and its clinical utility explored at a site in which the transmission of Lyme disease is intense. This collaborative project links an academic laboratory that has been prominent in work on the biology of Lyme disease with a commercial laboratory experienced in the development and marketing of diagnostic products.

Agency
National Institute of Health (NIH)
Institute
National Center for Infectious Diseases (CID)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43CI000015-01
Application #
3494120
Study Section
Special Emphasis Panel (SSS (B5))
Project Start
1991-09-30
Project End
1992-06-30
Budget Start
1991-09-30
Budget End
1992-06-30
Support Year
1
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Immunetics, Inc.
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02210