We propose to develop a light source having a spectrum that spans the visible wavelengths, with a beam quality similar to a laser. Our goal is to cover the wavelengths from 400 nm- 700 nm, with at least 1 mW in any 1 nm slice of the spectrum. The light source will be based on an inexpensive diode-pumped mode-locked laser, the output of which is spectrally broadened into a continuum by a highly nonlinear, single-mode, fused-silica fiber. The output of the fiber will be pulses of diffraction-limited white light, with a pulse repetition rate near 100 MHz. Such a high repetition rate is equivalent to continuous light for virtually all instrument applications. Such a source would have many laboratory uses, for example in fluorescence imaging. The spectrum of the proposed source could be filtered to obtain a laser-like beam at any desired visible wavelength. This flexibility would make fluorescence confocal microscopes much more powerful tools, since they could be used at any excitation wavelength.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43EB003326-01A1
Application #
6833603
Study Section
Special Emphasis Panel (ZRG1-SSS-U (10))
Program Officer
Zhang, Yantian
Project Start
2004-09-24
Project End
2005-05-31
Budget Start
2004-09-24
Budget End
2005-05-31
Support Year
1
Fiscal Year
2004
Total Cost
$81,354
Indirect Cost
Name
Lightwave Electronics Corporation
Department
Type
DUNS #
City
Mountain View
State
CA
Country
United States
Zip Code
94043