The broad, long term objective of this proposal is to overcome optical design, ergonomical, and cosmetic obstacles that stand in the way of innovative lens designs for low vision enhancement. Specifically, we have chosen to carry forward the work on field expansion for Homonymous Hemianopia proposed by Dr. Eli Peli of the Schepens Eye Research Institute. The design, incorporating 40 diopter prisms in upper and lower segments, has the potential of helping the one million Americans afflicted with this condition annually. A novel oblique prism arrangement expanding vision further into the central field would be made possible by the new proposed design. Earlier use of temporary press-on Fresnel prisms and a few elementary, but functional handmade prototypes indicate the potential success of this concept, however, the lenses are not cosmetically acceptable and the cost of the lenses is excessive putting them beyond the reach of most who could benefit. Based on clinical studies, we intend to determine the optimal values of various parameters of these new prism segment lenses to make them suitable for mass production. This would reduce manufacturing time and cost by up to 70% and provide a safe, durable, and cosmetically acceptable lens to improve patient mobility. We will evaluate the feasibility of manufacturing the new design with these parameters. In phase 2 we envision developing a final lens design, based on results or our phase 1 feasibility testing, a simple fitting protocol, also through clinical trials, which will allow any practitioner to fit these lenses as easily as a flat top bifocal, making them widely available.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43EY014723-01
Application #
6619339
Study Section
Special Emphasis Panel (ZEY1-VSN (02))
Program Officer
Helmsen, Ralph J
Project Start
2003-04-01
Project End
2005-03-31
Budget Start
2003-04-01
Budget End
2004-03-31
Support Year
1
Fiscal Year
2003
Total Cost
$263,709
Indirect Cost
Name
Chadwick Optical, Inc.
Department
Type
DUNS #
051320125
City
White River Junction
State
VT
Country
United States
Zip Code
05001
Bowers, Alex R; Keeney, Karen; Peli, Eli (2014) Randomized crossover clinical trial of real and sham peripheral prism glasses for hemianopia. JAMA Ophthalmol 132:214-22
Bowers, Alex R; Keeney, Karen; Peli, Eli (2008) Community-based trial of a peripheral prism visual field expansion device for hemianopia. Arch Ophthalmol 126:657-64