It is estimated that 220,000 people suffer cardiac arrest each year in the US, of whom only 10,000 survive to hospital discharge. The number of survivors could increase 10-fold if paramedical attention and/or defibrillation were available within a new minutes of the attack. It is the goal of our company to develop and deploy new and innovative technology that improves survival of cardiac arrest by lessening the time to treatment. This is a proposal to design, develop, and test the feasibility of an implanted monitor that notifies bystanders and emergency medical services (EMS) of an incipient cardiac arrest and/or acute myocardial ischemia. Such notification can shorten materially the time to defibrillation of most witnessed, and all unwitnessed, episodes of cardiac arrest, thereby improving survival manyfold. The tiny device will automatically detect the lethal event and signal transcutaneously to a cellphone-size purse, pocket, belt-worn or night stand unit which gives voice instructions to bystanders, spouse, or other witnesses and transmits victim location to the nearest EMS. Candidates for the implanted device are those readily identifiable cardiac patients whose medical condition and/or history puts them at particularly high risk of cardiac arrest.

Proposed Commercial Applications

The monitor/alarm will address the problem of 220,000 cardiac arrests a year of which only 3-5% presently survive. An implanted monitor/alarm could speed life saving rescuers to a victim of cardiac arrest, summon EMS automatically, and provide instant victim location. The US market for such a device could exceed 100,000 units, as our ability to define the population at risk improves.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43HL069608-01A1
Application #
6486857
Study Section
Special Emphasis Panel (ZRG1-SSS-W (10))
Program Officer
Goldberg, Suzanne H
Project Start
2002-06-01
Project End
2004-05-30
Budget Start
2002-06-01
Budget End
2003-05-30
Support Year
1
Fiscal Year
2002
Total Cost
$150,000
Indirect Cost
Name
Aj Medical Devices, Inc.
Department
Type
DUNS #
City
Wilmette
State
IL
Country
United States
Zip Code
60091
Song, Zhendong; Jenkins, Janice; Burke, Martin et al. (2004) The feasibility of ST-segment monitoring with a subcutaneous device. J Electrocardiol 37 Suppl:174-9