X-ray transmission radiography is an important diagnostic tool for a wide variety of conditions. The need for improved resolution radiographs with minimal patient exposure has long been recognized for many areas of radiological imaging. X-ray film alone used as the recording media is capable of producing high quality radiographs. However, due to sensitivity limitations of the film to X-rays, it is necessary to use X-ray sensitive phosphor screens. The use of conventional film-screen necessitate a tradeoff between the thickness and spatial resolution due to lateral light spreading. Current x-ray film screens therefore limit the effectiveness of many radiographic procedures and necessitate unduly high patient exposure. The Phase I program demonstrated the feasibility of a new concept of producing X-ray convertor screens. During this program, novel convertor films of 5 cm x 5 cm were produced which had the high X-ray sensitivity, excellent light output and uniformity indicated that it will be possible to produce convertor screens with over 95% stopping power for 28 keV X-rays, light output at least 150% that of presently used convertors and limiting spatial resolution better than 20 Ip/mm. During phase II, we shall complete the development of the improved large- area film-cassette based on this new convertor screen and use it in film cassettes to measure large area phantoms. This work will involve methods of producing the large area X-ray converters required for standard mammographic format films.

Proposed Commercial Applications

Besides the enormous clinical X-ray imaging market, the proposed detector would find widespread use in instrumentation wherever high resolution X-ray detectors are used. X-ray imaging instruments currently have a very large commercial market. They may be applied to non-destructive testing systems, diffraction instruments, basic physics research, and other medical imaging systems.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
Project #
2R44CA063857-02
Application #
2105980
Study Section
Special Emphasis Panel (ZRG7-SSS-7 (26))
Project Start
1994-06-01
Project End
1997-06-30
Budget Start
1995-07-01
Budget End
1996-06-30
Support Year
2
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Radiation Monitoring Devices, Inc.
Department
Type
DUNS #
073804411
City
Watertown
State
MA
Country
United States
Zip Code
02472