Phase II application abstract): The project proposed in this Phase II application has a broad, long-term objective to develop a user friendly software program, VOL-3D, which models and evaluates the optics of a real and/or user-defined eye and stores analysis outcomes in a relational data base. The software program will use ray tracing and traditional paraxial analysis of the composite model eye. The program will allow, but not require, exam data from commercially available ophthalmic instruments as input in the construction of the model of an individual's eye.
The specific aims of Phase II are to capitalize on the Phase I demonstration of feasibility to: 1) expand the library of callable functions; 2) obtain independent verification of modeling assumptions and implementation; 3) optimize the user friendliness; and 4) develop ophthalmic instrumentation interface software modules. This program is related to human health in that it will provide: 1) outcome predictions of surgical and non-surgical interventions; 2) development and optimization of strategies for the optical correction of the eye; 3) education of clinicians and students of visual science; and 4) fundamental research into limitations of the dioptrics of the eye.

Proposed Commercial Applications

The software program VOL-3D will be purchased and used by clinicians, vision researchers, owners of corneal topography systems, students, teachers, and companies who are attempting to understand in a predictive manner the optical properties of the eye.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
Project #
5R44EY011681-03
Application #
6179159
Study Section
Special Emphasis Panel (ZRG1-VISB (02))
Program Officer
Fisher, Richard S
Project Start
1998-07-01
Project End
2001-08-30
Budget Start
2000-04-01
Budget End
2001-08-30
Support Year
3
Fiscal Year
2000
Total Cost
$311,835
Indirect Cost
Name
Sarver and Associates, Inc.
Department
Type
DUNS #
010030026
City
Carbondale
State
IL
Country
United States
Zip Code
62902
Applegate, Raymond A; Ballentine, Charles; Gross, Hillery et al. (2003) Visual acuity as a function of Zernike mode and level of root mean square error. Optom Vis Sci 80:97-105
Applegate, Raymond A; Sarver, Edwin J; Khemsara, Vic (2002) Are all aberrations equal? J Refract Surg 18:S556-62
Doshi, J B; Sarver, E J; Applegate, R A (2001) Schematic eye models for simulation of patient visual performance. J Refract Surg 17:414-9