The major goal of Phase I is to finish development of the CoagCare(TM) System, an Internet-enabled system for the automated management of oral anticoagulation therapy with warfarin. ZyCare, Inc. is developing detailed specifications for the system and is currently coding the software for the system. One U.S. patent has already been awarded for the CoagCare(TM) System and another is pending. CoagCare(TM) has two essential components for treatment delivery, the CoagCare(TM) Patient Module (CPM) and the CoagCare(TM) Caregiver Module (CCM) for use by healthcare professionals managing patients. Software for the CPM and CCM will run on a browser that can be accessed from a variety of platforms with an Internet connection. During Phase I, formal detailed specifications and software for the CPM and CCM coding will be completed. We will also develop a specification for special evaluation software for the CPM. This software, the CPM Professional Assessment System (CPM-PAS), will allow professionals who manage anticoagulation therapy to formally evaluate the interface, content, and decision-making performed by the CPM and assist software engineers in validating the core functions of the CPM during Phase II. The major milestones we plan to achieve before beginning Phase II are to complete the initial versions of the CPM, CCM and to develop the specification for the CPM-PAS for formal validation of the CoagCare(TM) system.

Proposed Commercial Applications

The CoagCare (TM) System described promises to revolutionize the management of warfarin therapy by automating patient self-management and physician supervision.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
Project #
1R44HL066888-01
Application #
6299123
Study Section
Special Emphasis Panel (ZRG1-SSS-9 (28))
Program Officer
Link, Rebecca P
Project Start
2001-03-01
Project End
2001-08-31
Budget Start
2001-03-01
Budget End
2001-08-31
Support Year
1
Fiscal Year
2001
Total Cost
$121,712
Indirect Cost
Name
Zycare, Inc.
Department
Type
DUNS #
103815259
City
Chapel Hill
State
NC
Country
United States
Zip Code
27514
O'Shea, Susan I; Arcasoy, Murat O; Samsa, Gregory et al. (2008) Direct-to-patient expert system and home INR monitoring improves control of oral anticoagulation. J Thromb Thrombolysis 26:14-21