Corteks proposes to develop a high speed, compact, moderately priced, magnetic neural stimulator for neurophysiology. The device will overcome major limitations of presently available magnetic stimulators by permitting restriction of stimulation to limited regions of neural tissue, and by allowing stimulation at higher rates. Major clinical applications will include diagnostic and intraoperative evaluation of efferent pathways, as well as possible in vivo selective fiber stimulation. The feasibility of stimulating restricted areas of neural tissue, and achieving high rates of stimulation was demonstrated in Phase I. In Phase II, we will perform experiments to determine optimum stimulation parameters, build an optimized stimulator, and test the device for both effectiveness and safety.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
Project #
5R44NS024924-03
Application #
3509191
Study Section
Special Emphasis Panel (SSS (N))
Project Start
1987-03-01
Project End
1991-09-30
Budget Start
1990-04-01
Budget End
1991-09-30
Support Year
3
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Alacron, Inc.
Department
Type
DUNS #
City
Chappaqua
State
NY
Country
United States
Zip Code
10514
Sgro, J A; Ghatak, N R; Stanton, P C et al. (1991) Repetitive high magnetic field stimulation: the effect upon rat brain. Electroencephalogr Clin Neurophysiol Suppl 43:180-5
Sgro, J; Stanton, P; Emerson, R (1991) Theoretical and practical performance of magnetic stimulators and coils. Electroencephalogr Clin Neurophysiol Suppl 43:279-83