Precise and flexible stimulus delivery and experimental control (SDEC) are essential for studies of perception and higher-cognitive functions. We have developed Presentation, a Windows SDEC program that delivers complex multimodal stimuli and monitors responses with precise timing. We now request Phase II support to add innovative new features to Presentation including (1) Adaptive stimulus delivery using the Presentation Control Language (PCL). PCL permits stimuli to be altered in real time based on performance or physiological responses, allowing automated adjustments in task difficulty, computer-controlled determination of neuronal receptive fields, and frame-by-frame display control important for computer-based neuro-rehabilitation. ((2) Graphic and audio stimulus generation using high-level Direct3D and DirectSound commands. These will permit auditory and visual stimuli to be defined and manipulated in 3D space. Stereovision and tactile stimulation capabilities will also be added sing DirectX 8.0 utilities. (3) A stimulus generation module interface (SGMI), permitting user programs to present custom stimuli during Presentation experiments. (4) Real-time streaming video with precise frame-by-frame control, making possible experiments with digitized and synthesized video sequences; (5) Easy-to-use tools for experiment creation and analysis to facilitate the development and analysis of experimental protocols. These additions will make Presentation an unexcelled SDEC platform for Phase III product launch.

Proposed Commercial Applications

Te proposed project will lead directly to a commercial PC-based stimulus delivery / experimental control software package.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
Project #
2R44NS040623-02
Application #
6404122
Study Section
Special Emphasis Panel (ZRG1-VISB (10))
Program Officer
Heetderks, William J
Project Start
2000-09-15
Project End
2003-08-31
Budget Start
2001-09-15
Budget End
2002-08-31
Support Year
2
Fiscal Year
2001
Total Cost
$403,832
Indirect Cost
Name
Neurobehavioral Systems, Inc.
Department
Type
DUNS #
City
Albany
State
CA
Country
United States
Zip Code
94706