Systemic barriers to engaging historically underrepresented (HU) students not only limit innovation and productivity in biomedical research, they perpetuate social inequities. To overcome these barriers to effective, equitable biomedical research that benefits all populations, the overall goal of the SF BUILD II project is to sustain promising climate transformation efforts and disseminate those found to be effective. Toward this end, promising efforts from SF BUILD I will be maintained and tested at both the primary institution, San Francisco State University (SF State), and its research partner, the University of California, San Francisco (UCSF). SF BUILD?s key innovation is its focus on changing institutions rather than individual students, to make the path to a research career more inviting. In SF BUILD I, an approach guided by the Signaling Affirmation for Equity (SAFE) model achieved progress in creating affirming and inclusive teaching and research environments. SAFE is grounded in social science theory and evidence of triggers that cause HU students to exit science, as well as social contextual cues that mitigate triggers, to improve student retention and success. Quantitative data from SF BUILD I show that growing a SAFE environment mitigates stereotype threat, promotes science efficacy, and increases science identity. As a result, participating HU students report a greater intent to pursue biomedical research careers. In SF BUILD II, inclusive and effective approaches to teaching and research training will be sustained and disseminated, and students? meaningful engagement in the biomedical research workforce will continue to be affirmed. Systemic affirmation will take place through counter-stereotyping and microaffirmation activities in the classroom, and by engaging HU students in peer mentoring and research activities that ?give back? to the communities from which they come. In addition, data on longer-term outcomes, such as graduate school matriculation and retention, will be gathered and evaluated. The SF BUILD approach capitalizes on the institutional history and mission of SF State, a predominantly undergraduate institution that has attained national prominence for preparing HU students for biomedical research careers. SF BUILD II aims to leverage SF State?s record of success to create agents of change who will build the capacity for biomedical research that benefits all populations. This goal is also a critical focus of UCSF, which?through its School of Medicine?s Differences Matter Initiative, established during SF BUILD I?aims to become the most diverse, equitable, and inclusive academic medical system in the country. The proposed work is significant because, working together, SF State and UCSF expect SF BUILD II to result in a national, large-scale model for creating collaborative, affirming, and inclusive teaching and research environments for HU undergraduates. In this way, HU students across the country will be able to successfully transition to premiere research universities and become the agents of change essential for a new, more inclusive approach to biomedical research.

Public Health Relevance

TO PUBLIC HEALTH: SF BUILD II is relevant to public health because enhancing the diversity of biomedical researchers will lead to scientific innovation and a more skilled workforce focused on equitable and inclusive health-related outcomes for all populations. Ultimately, disseminating the SF BUILD approach will advance the nation?s capacity to address and eliminate health inequities; thus, the proposed work is relevant to NIH?s promise to turn discovery into health for all U.S. populations.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Linked Education Project (RL5)
Project #
5RL5GM118984-07
Application #
9974526
Study Section
Special Emphasis Panel (ZGM1)
Program Officer
Falcon-Morales, Edgardo
Project Start
2014-09-26
Project End
2024-06-30
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
7
Fiscal Year
2020
Total Cost
Indirect Cost
Name
San Francisco State University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
942514985
City
San Francisco
State
CA
Country
United States
Zip Code
94132
Mak, Angel C Y; White, Marquitta J; Eckalbar, Walter L et al. (2018) Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma. Am J Respir Crit Care Med 197:1552-1564
Estrada, Mica; Eroy-Reveles, Alegra; Matsui, John (2018) The Influence of Affirming Kindness and Community on Broadening Participation in STEM Career Pathways. Soc Issues Policy Rev 12:258-297
Zeiger, Andrew M; White, Marquitta J; Eng, Celeste et al. (2018) Genetic Determinants of Telomere Length in African American Youth. Sci Rep 8:13265
Sun, Xiaobo; Gao, Jingjing; Jin, Peng et al. (2018) Optimized distributed systems achieve significant performance improvement on sorted merging of massive VCF files. Gigascience 7:
Estrada, Mica; Eroy-Reveles, Alegra; Ben-Zeev, Avi et al. (2017) Enabling full representation in science: the San Francisco BUILD project's agents of change affirm science skills, belonging and community. BMC Proc 11:25
Chitewere, Tendai; Shim, Janet K; Barker, Judith C et al. (2017) How Neighborhoods Influence Health: Lessons to be learned from the application of political ecology. Health Place 45:117-123
Ramirez, Julio; Elmofty, May; Castillo, Esperanza et al. (2017) Evaluation of cortisol and telomere length measurements in ethnically diverse women with breast cancer using culturally sensitive methods. J Community Genet 8:75-86
Akom, Antwi; Shah, Aekta; Nakai, Aaron et al. (2016) Youth Participatory Action Research (YPAR) 2.0: how technological innovation and digital organizing sparked a food revolution in East Oakland. Int J Qual Stud Educ 29:1287-1307
Ardila-Mantilla, Federico (2016) Todos Cuentan: Cultivating Diversity in Combinatorics. Not Am Math Soc 63:1164-1170
Trujillo, Gloriana; Aguinaldo, Pauline G; Anderson, Chelsie et al. (2015) Near-peer STEM Mentoring Offers Unexpected Benefits for Mentors from Traditionally Underrepresented Backgrounds. Perspect Undergrad Res Mentor 4: