This is an application for a continuing SCORE Program at New Mexico State University (NMSU), Las Cruces. A goal of NMSU is to expand research at the institution for participation by ethnic minority students who desire to pursue careers in the biomedical science disciplines. The proposed SCORE Program has as its goals: (i) To transition, within the next four years, 74% of the investigators of regular SCORE subprojects in this application to competition for R01 funding from NIH. (ii) To enhance within the next four years, the publication records of all investigators of SCORE subprojects, who are in their second cycle of funding, to a minimum of 33% more research manuscripts per year in peer-reviewed, refereed journals. (iii) To significantly improve the capabilities of NMSU to conduct biomedically-relevant research through development of core research facilities. (iv) To improve the capacity of NMSU to self-evaluate, assess, and monitor the SCORE Program for the purpose of institutional self-study, program review, support of MORE Program missions, and internal improvement of research management. This application contains research proposals for nineteen research subprojects and three pilot subprojects. Disciplines represented among these proposals include Agronomy, Animal Science, Biochemistry, Biology, Chemistry, Molecular Biology, Microbiology and Psychology. The research topics of proposed projects include: mitosis and cytokinesis in animal cells, sensory organogenesis during inner ear development, genomic interactions of the growth hormone axis and leptin, pathogenicity in symbiotic vibrios, transcription factors in myogenic cells of electric fish, translational control of hepatitis C virus, adaptations of pigeons and rats to hypoxia, transmission of the pathogen, Cryptosporidium parvum, bacteriocide tolerance of Staphylococcus aureus, regulation of glutamine synthetase, programmed cell death studied by RNAi, electric and mechanical properties of bio-macromolecules, metal ion chelators for biomedical applications, high-valence iron complexes as models for non-heme iron proteins, chemical synthesis of radiopharmaceuticals, transcription regulation of secondary metabolism, organic synthesis of novel heterocyclic and aromatic compounds, transcriptional profiling of drought and salt tolerance in plants, selective binding of enantiomers by clays, and infant learning gauged by cortisol and behavioral synchrony. This SCORE Program will continue a 29-year MBRS Program which has advanced 351 minority students (approximately 81% of B.S.-graduated participants) to post-baccalaureate training, 72 earning Ph.D. degrees, since 1974.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
3S06GM008136-33S2
Application #
7687742
Study Section
Special Emphasis Panel (ZGM1-MBRS-8 (04))
Program Officer
Poodry, Clifton A
Project Start
1997-03-01
Project End
2009-05-31
Budget Start
2007-06-01
Budget End
2009-05-31
Support Year
33
Fiscal Year
2008
Total Cost
$146,161
Indirect Cost
Name
New Mexico State University Las Cruces
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
173851965
City
Las Cruces
State
NM
Country
United States
Zip Code
88003
Pfister, Katherine; Shook, David R; Chang, Chenbei et al. (2016) Molecular model for force production and transmission during vertebrate gastrulation. Development 143:715-27
Edelaar, Pim; Roques, Severine; Hobson, Elizabeth A et al. (2015) Shared genetic diversity across the global invasive range of the monk parakeet suggests a common restricted geographic origin and the possibility of convergent selection. Mol Ecol 24:2164-76
Keyhaninejad, Neda; Curry, Jeanne; Romero, Joslynn et al. (2014) Fruit specific variability in capsaicinoid accumulation and transcription of structural and regulatory genes in Capsicum fruit. Plant Sci 215-216:59-68
Richins, Richard D; Kilcrease, James; Rodgriguez-Uribe, Laura et al. (2014) Carotenoid Extraction and Quantification from Capsicum annuum. Bio Protoc 4:
Unguez, Graciela A (2013) Electric fish: new insights into conserved processes of adult tissue regeneration. J Exp Biol 216:2478-86
Cuaron, Jesus A; Dulal, Santosh; Song, Yang et al. (2013) Tea tree oil-induced transcriptional alterations in Staphylococcus aureus. Phytother Res 27:390-6
Güth, Robert; Pinch, Matthew; Unguez, Graciela A (2013) Mechanisms of muscle gene regulation in the electric organ of Sternopygus macrurus. J Exp Biol 216:2469-77
Guerrero-Ferreira, Ricardo; Gorman, Clayton; Chavez, Alba A et al. (2013) Characterization of the bacterial diversity in Indo-West Pacific loliginid and sepiolid squid light organs. Microb Ecol 65:214-26
Young, Jennifer A; Karmakar, Sukhen; Jacobs, Hollie K et al. (2012) Synthetic approaches to mixed ligand chelators on t-butylphenol-formaldehyde oligomer (PFO) platforms. Tetrahedron 68:10030-10039
Ortega, Jose Luis; Wilson, Olivia L; Sengupta-Gopalan, Champa (2012) The 5' untranslated region of the soybean cytosolic glutamine synthetase ?(1) gene contains prokaryotic translation initiation signals and acts as a translational enhancer in plants. Mol Genet Genomics 287:881-93

Showing the most recent 10 out of 106 publications