Abstract

The University of Texas at Brownsville and Texas Southmost College (UTB/TSC) is a minority serving institution committed to develop biomedical research. Programs sponsored by the Minority Biomedical Research Services (MBRS) of the National Institutes of Health will play a critical role in complementing UTB/TSC resources to develop these activities. SCORE funds will be critical to develop a strong core of scientists with competitive research programs in biomedicine at UTB/TSC. Described in this proposal is the current situation in our institution, the needs for the SCORE program, and the impact that this program will have on UTB/TSC academic life. This general section is followed by the individual research projects. The proposed research focuses in two thematic areas: neuroscience and infectious diseases. These areas have been identified as priorities in UTB/TSC's strategic plan due to their impact on both university and community life. Other areas of research, also identified as critical, will be added during the first 18 months of the grant period when qualified investigators are recruited. The funding of these projects will substantially increase the competitiveness and research capabilities of UTB/TSC and will provide the foundation for developing a biomedical research center.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
5S06GM068855-04
Application #
7118701
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Tupas, Jermelina
Project Start
2003-08-01
Project End
2008-07-31
Budget Start
2006-08-01
Budget End
2008-07-31
Support Year
4
Fiscal Year
2006
Total Cost
$823,712
Indirect Cost

  Institution

Name
University/Texas Brownsville & Southmost Coll
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
800187965
City
Brownsville
State
TX
Country
United States
Zip Code
78520

  Publications

Unterweger, Daniel; Miyata, Sarah T; Bachmann, Verena et al. (2014) The Vibrio cholerae type VI secretion system employs diverse effector modules for intraspecific competition. Nat Commun 5:3549
Cox, N; Toro, B; Pacheco-Otalora, L F et al. (2014) An endoplasmic reticulum trafficking signal regulates surface expression of ?4 subunit of a voltage- and Ca²?-activated K? channel. Brain Res 1553:12-23
Cooley, Benjamin J; Thatcher, Travis W; Hashmi, Sara M et al. (2013) The extracellular polysaccharide Pel makes the attachment of P. aeruginosa to surfaces symmetric and short-ranged. Soft Matter 9:3871-3876
Gonzales, Miguel F; Brooks, Teresa; Pukatzki, Stefan U et al. (2013) Rapid protocol for preparation of electrocompetent Escherichia coli and Vibrio cholerae. J Vis Exp :
Durán-González, Jorge; Michi, Edna D; Elorza, Brisa et al. (2013) Amyloid ? peptides modify the expression of antioxidant repair enzymes and a potassium channel in the septohippocampal system. Neurobiol Aging 34:2071-6
Colom, L V; Castaneda, M T; Aleman, D et al. (2013) Memantine protects cholinergic and glutamatergic septal neurons from A?1-40-induced toxicity. Neurosci Lett 541:54-7
Unterweger, Daniel; Kitaoka, Maya; Miyata, Sarah T et al. (2012) Constitutive type VI secretion system expression gives Vibrio cholerae intra- and interspecific competitive advantages. PLoS One 7:e48320
Colom, Luis V; Castañeda, Maria T; Bañuelos, Cristina et al. (2010) Medial septal beta-amyloid 1-40 injections alter septo-hippocampal anatomy and function. Neurobiol Aging 31:46-57
Shokri, Leila; Marintcheva, Boriana; Eldib, Mootaz et al. (2008) Kinetics and thermodynamics of salt-dependent T7 gene 2.5 protein binding to single- and double-stranded DNA. Nucleic Acids Res 36:5668-77
Bina, Xiaowen R; Provenzano, Daniele; Nguyen, Nathalie et al. (2008) Vibrio cholerae RND family efflux systems are required for antimicrobial resistance, optimal virulence factor production, and colonization of the infant mouse small intestine. Infect Immun 76:3595-605

Showing the most recent 10 out of 19 publications