Dillard University proposes to involve three (3) faculty and nine (9) students in biomedical research projects as follows: Water Balance in the American Cockroach. Liquid scintillation counting of tritiated water used to trace water movements will be combined with column chromatography and electrophoresis of body fluids, bioassay of proteins from body fluids and electron microscopy of neurosecretory tissues to determine the role of the frontal ganglion in control of water balance in the American cockroach. Skin Testing of Fungal Antigens. Skin test reactions of patients with mycotic infections will be compared with those of """"""""normal"""""""" populations such as nursing students and workers in nurseries and other related areas. Soil collections, cultures and inoculations into mice to delineate microfoci and to uncover the perfect stage of Sporothrix schenckii will be undertaken. Improved immunologic methods of diagnosis of fungal diseases will be sought. Characterization of Bovine Corneal Mucoproteins. Corneal Mucoproteins established as the primary contributor to hydration of the cornea will be characterized via electrophoretic fractionation. Concentration and hydration gradients will be identified in bovine corneas. The role of mucoproteins in the orderly disposition of collagen fibrils will be investigated and their role in corneal transparency ascertained.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
5S06RR008064-15
Application #
3513871
Study Section
General Research Support Program Advisory Committee (GRS)
Project Start
1977-06-01
Project End
1988-08-31
Budget Start
1986-09-01
Budget End
1987-08-31
Support Year
15
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Dillard University
Department
Type
Schools of Arts and Sciences
DUNS #
062665468
City
New Orleans
State
LA
Country
United States
Zip Code
70122
Verrett, J M; Green, K B; Gamble, L M et al. (1987) A hemocoelic Candida parasite of the American cockroach (Dictyoptera: Blattidae). J Econ Entomol 80:1205-12