Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biomedical Research Support Grants (S07)
Project #
2S07RR005451-28
Application #
3515249
Study Section
(NSS)
Project Start
1979-04-01
Project End
1990-03-31
Budget Start
1989-04-01
Budget End
1990-03-31
Support Year
28
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
Schools of Public Health
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
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McKnight, J L; Doerr, M; Zhang, Y (1994) An 85-kilodalton herpes simplex virus type 1 alpha trans-induction factor (VP16)-VP13/14 fusion protein retains the transactivation and structural properties of the wild-type molecule during virus infection. J Virol 68:1750-7
McKnight, J L; Cen, H; Riddler, S A et al. (1994) EBV gene expression, EBNA antibody responses and EBV+ peripheral blood lymphocytes in post-transplant lymphoproliferative disease. Leuk Lymphoma 15:9-16
Cen, H; McKnight, J L (1994) EBV-immortalized isogenic human B-cell clones exhibit differences in DNA-protein complex formation on the BZLF1 and BRLF1 promoter regions among latent, lytic and TPA-activated cell lines. Virus Res 31:89-107
Riddler, S A; Breinig, M C; McKnight, J L (1994) Increased levels of circulating Epstein-Barr virus (EBV)-infected lymphocytes and decreased EBV nuclear antigen antibody responses are associated with the development of posttransplant lymphoproliferative disease in solid-organ transplant recipients. Blood 84:972-84
Tosato, G; Jones, K; Breinig, M K et al. (1993) Interleukin-6 production in posttransplant lymphoproliferative disease. J Clin Invest 91:2806-14
Cen, H; Williams, P A; McWilliams, H P et al. (1993) Evidence for restricted Epstein-Barr virus latent gene expression and anti-EBNA antibody response in solid organ transplant recipients with posttransplant lymphoproliferative disorders. Blood 81:1393-403
Zhang, Y; McKnight, J L (1993) Herpes simplex virus type 1 UL46 and UL47 deletion mutants lack VP11 and VP12 or VP13 and VP14, respectively, and exhibit altered viral thymidine kinase expression. J Virol 67:1482-92
Koros, A M; Tobin, M J; Epperly, M W et al. (1993) 186Rhenium-HNK1 monoclonal antibody targets human small cell lung cancer cells in athymic nude mice: rapid screening model for therapy. Anticancer Res 13:1953-6
Bunker, C H; Ukoli, F A; Nwankwo, M U et al. (1992) Factors associated with hypertension in Nigerian civil servants. Prev Med 21:710-22

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