Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biomedical Research Support Shared Instrumentation Grants (S10)
Project #
1S10RR017992-01A1
Application #
6973246
Study Section
Special Emphasis Panel (ZRG1-SSS-A (30))
Project Start
2004-04-01
Project End
2005-03-31
Budget Start
2004-04-01
Budget End
2005-03-31
Support Year
1
Fiscal Year
2004
Total Cost
$82,165
Indirect Cost
Name
University of Medicine & Dentistry of NJ
Department
Pharmacology
Type
Schools of Medicine
DUNS #
617022384
City
Piscataway
State
NJ
Country
United States
Zip Code
08854
Sleat, David E; Sun, Pengling; Wiseman, Jennifer A et al. (2013) Extending the mannose 6-phosphate glycoproteome by high resolution/accuracy mass spectrometry analysis of control and acid phosphatase 5-deficient mice. Mol Cell Proteomics 12:1806-17
Della Valle, Maria Cecilia; Sleat, David E; Zheng, Haiyan et al. (2011) Classification of subcellular location by comparative proteomic analysis of native and density-shifted lysosomes. Mol Cell Proteomics 10:M110.006403
Xu, Su; Sleat, David E; Jadot, Michel et al. (2010) Glial fibrillary acidic protein is elevated in the lysosomal storage disease classical late-infantile neuronal ceroid lipofuscinosis, but is not a component of the storage material. Biochem J 428:355-62
Qian, Yi; Lee, Intaek; Lee, Wang-Sik et al. (2010) Functions of the alpha, beta, and gamma subunits of UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase. J Biol Chem 285:3360-70
Sleat, David E; Ding, Lin; Wang, Shudan et al. (2009) Mass spectrometry-based protein profiling to determine the cause of lysosomal storage diseases of unknown etiology. Mol Cell Proteomics 8:1708-18
Guhaniyogi, Jayita; Sohar, Istvan; Das, Kalyan et al. (2009) Crystal structure and autoactivation pathway of the precursor form of human tripeptidyl-peptidase 1, the enzyme deficient in late infantile ceroid lipofuscinosis. J Biol Chem 284:3985-97
Trojer, Patrick; Zhang, Jin; Yonezawa, Masato et al. (2009) Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins. J Biol Chem 284:8395-405
Sleat, David E; Della Valle, Maria Cecilia; Zheng, Haiyan et al. (2008) The mannose 6-phosphate glycoprotein proteome. J Proteome Res 7:3010-21
Pungaliya, Pooja; Kulkarni, Diptee; Park, Hye-Jin et al. (2007) TOPORS functions as a SUMO-1 E3 ligase for chromatin-modifying proteins. J Proteome Res 6:3918-23
Sleat, David E; Zheng, Haiyan; Lobel, Peter (2007) The human urine mannose 6-phosphate glycoproteome. Biochim Biophys Acta 1774:368-72

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