Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Biomedical Research Support Shared Instrumentation Grants (S10)
Project #
1S10RR019355-01
Application #
6973622
Study Section
Special Emphasis Panel (ZRG1-SSS-A (30))
Project Start
2004-03-01
Project End
2005-02-28
Budget Start
2004-03-01
Budget End
2005-02-28
Support Year
1
Fiscal Year
2004
Total Cost
$112,919
Indirect Cost
Name
Weill Medical College of Cornell University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
060217502
City
New York
State
NY
Country
United States
Zip Code
10065
Xu, Guoqiang; Jiang, Xiaogang; Jaffrey, Samie R (2013) A mental retardation-linked nonsense mutation in cereblon is rescued by proteasome inhibition. J Biol Chem 288:29573-85
Xu, Guoqiang; Shin, Sung Bin Y; Jaffrey, Samie R (2011) Chemoenzymatic labeling of protein C-termini for positive selection of C-terminal peptides. ACS Chem Biol 6:1015-20
Xu, Guoqiang; Jaffrey, Samie R (2010) N-CLAP: global profiling of N-termini by chemoselective labeling of the alpha-amine of proteins. Cold Spring Harb Protoc 2010:pdb.prot5528
Xu, Guoqiang; Paige, Jeremy S; Jaffrey, Samie R (2010) Global analysis of lysine ubiquitination by ubiquitin remnant immunoaffinity profiling. Nat Biotechnol 28:868-73
Hao, Gang; Wang, Danchen; Gu, Jane et al. (2009) Neutral loss of isocyanic acid in peptide CID spectra: a novel diagnostic marker for mass spectrometric identification of protein citrullination. J Am Soc Mass Spectrom 20:723-7
Xu, Guoqiang; Shin, Sung Bin Y; Jaffrey, Samie R (2009) Global profiling of protease cleavage sites by chemoselective labeling of protein N-termini. Proc Natl Acad Sci U S A 106:19310-5
Paige, Jeremy S; Xu, Guoqiang; Stancevic, Branka et al. (2008) Nitrosothiol reactivity profiling identifies S-nitrosylated proteins with unexpected stability. Chem Biol 15:1307-16
Upmacis, Rita K; Crabtree, Mark J; Deeb, Ruba S et al. (2007) Profound biopterin oxidation and protein tyrosine nitration in tissues of ApoE-null mice on an atherogenic diet: contribution of inducible nitric oxide synthase. Am J Physiol Heart Circ Physiol 293:H2878-87
Deeb, Ruba S; Hao, Gang; Gross, Steven S et al. (2006) Heme catalyzes tyrosine 385 nitration and inactivation of prostaglandin H2 synthase-1 by peroxynitrite. J Lipid Res 47:898-911
Deeb, Ruba S; Shen, Hao; Gamss, Caryn et al. (2006) Inducible nitric oxide synthase mediates prostaglandin h2 synthase nitration and suppresses eicosanoid production. Am J Pathol 168:349-62

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