The purpose of the proposed project, entitled """"""""The Ohio State University Clinical and Translational Research Informatics Training Program (CTRIP)"""""""", is to establish a novel and highly impactful Biomedical Informatics training initiative that focuses upon the emergent and rapidly growing sub-domains of Translational Bioinformatics (TBI) and Clinical Research Informatics (CRI). This program will leverage the unique scholarly and environmental strengths present at The Ohio State University Medical Center (OSUMC), and employ two well-established and highly successful pre- and post-doctoral training mechanisms present within The Ohio State University College of Medicine for degree granting purposes. Trainees will be involved in a combination of didactic and application-oriented instruction modalities, and will pursue independent research projects as a capstone to their curricula. The TBI track of the program will specifically focus upon pre-doctoral training, and combine core informatics competencies with a rigorous grounding in the biology of human disease. The CRI track of the program will specifically focus on post-doctoral training for individuals with terminal clinical degrees (e.g., MD, DO, or equivalent), and will similarly combine core informatics competencies with a rigorous grounding in clinical research methodology. The overall training program will house no more than six funded pre- and post-doctoral trainees at any given time. Our intent with the CTRIP program is to utilize an agile and highly innovative curricula development and evaluation plan, thus allowing for constant program optimization and adaptation to evolving trends and developments in the basic and applied Biomedical Informatics knowledge base.

Public Health Relevance

The Ohio State University Clinical and Translational Research Informatics Training Program (CTRIP) The purpose of the proposed project, entitled The Ohio State University Clinical and Translational Research Informatics Training Program (CTRIP) is to establish a Biomedical Informatics training initiative that focuses upon the emergent and rapidly growing sub-domains of Translational Bioinformatics (TBI) and Clinical Research Informatics (CRI). This program will catalyze the formation and dissemination of an informatics workforce capable of advancing clinical and translational research in order to speed the process by which new basic science discoveries and translated into actionable therapies for human diseases.

Agency
National Institute of Health (NIH)
Institute
National Library of Medicine (NLM)
Type
Continuing Education Training Grants (T15)
Project #
5T15LM011270-02
Application #
8471773
Study Section
Special Emphasis Panel (ZLM1-AP-T (01))
Program Officer
Florance, Valerie
Project Start
2012-07-01
Project End
2017-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
2
Fiscal Year
2013
Total Cost
$245,539
Indirect Cost
$15,067
Name
Ohio State University
Department
Miscellaneous
Type
Schools of Medicine
DUNS #
832127323
City
Columbus
State
OH
Country
United States
Zip Code
43210
Wells, Rebecca; Kite, Bobbie; Breckenridge, Ellen et al. (2018) Community Mental Health Center Integrated Care Outcomes. Psychiatr Q 89:969-982
Nasser, Mohd W; Datta, Jharna; Nuovo, Gerard et al. (2018) Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1. J Biol Chem 293:12945
Abrams, Zachary B; Zucker, Mark; Wang, Min et al. (2018) Thirty biologically interpretable clusters of transcription factors distinguish cancer type. BMC Genomics 19:738
Sinicropi-Yao, Sara L; Amann, Joseph M; Lopez, David Lopez Y et al. (2018) Co-Expression Analysis Reveals Mechanisms Underlying the Varied Roles of NOTCH1 in NSCLC. J Thorac Oncol :
Sharpnack, Michael F; Ranbaduge, Nilini; Srivastava, Arunima et al. (2018) Proteogenomic Analysis of Surgically Resected Lung Adenocarcinoma. J Thorac Oncol 13:1519-1529
Motiwala, Tasneem; Majumder, Sarmila; Ghoshal, Kalpana et al. (2018) PTPROt inactivates the oncogenic fusion protein BCR/ABL and suppresses transformation of K562 cells. J Biol Chem 293:3589
Patterson, Emily S; Dewart, Courtney M; Stevenson, Kurt et al. (2018) A MIXED METHODS APPROACH TO TAILORING EVIDENCE-BASED GUIDANCE FOR ANTIBIOTIC STEWARDSHIP TO ONE MEDICAL SYSTEM. Proc Int Symp Hum Factors Ergon Healthc 7:224-231
Ding, Hao; Sharpnack, Michael; Wang, Chao et al. (2018) Integrative cancer patient stratification via subspace merging. Bioinformatics :
Badawi, Mohamed; Kim, Jihye; Dauki, Anees et al. (2018) CD44 positive and sorafenib insensitive hepatocellular carcinomas respond to the ATP-competitive mTOR inhibitor INK128. Oncotarget 9:26032-26045
Latchana, Nicholas; DiVincenzo, Mallory J; Regan, Kelly et al. (2018) Alterations in patient plasma microRNA expression profiles following resection of metastatic melanoma. J Surg Oncol 118:501-509

Showing the most recent 10 out of 38 publications