This application requests continued funding for our highly successful program of Research Training in the Dementias of Aging. This program, which began in 1987, teaches postdoctoral physicians and psychologists how to conduct high quality research on disorders of great public health significance among the elderly. Most of the research training is the context of currently-funded projects at the Johns Hopkins School of Medicine. These include clinical and population-based surveys, longitudinal follow-up studies, laboratory-based case-control studies and clinical trials in Alzheimer's disease, Huntington's disease, Down's syndrome, delirium, and other syndromes of cognitive impairment. Research settings include the community, general hospital, and the nursing home, in addition to the laboratory. A large number of projects in the clinical neurosciences are currently available to fellows, with particular emphases on: instrument and measurement development; correlations between clinical/functional indicators and brain abnormalities revealed by neuroimaging methods; and application of genetic knowledge and methodology to the problems of dementing illnesses. Fellows receive two years of research tutelage and supervised experience, a full didactic program, and experience in the neuropsychiatry clinics. Past graduates of this training program have gone on to successful hospital and medical-school-based careers as clinical investigators.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Institutional National Research Service Award (T32)
Project #
5T32AG000149-14
Application #
6168573
Study Section
Neuroscience, Behavior and Sociology of Aging Review Committee (NBSA)
Program Officer
Anderson, Dallas
Project Start
1987-08-01
Project End
2002-04-30
Budget Start
2000-05-01
Budget End
2002-04-30
Support Year
14
Fiscal Year
2000
Total Cost
$1
Indirect Cost
Name
Johns Hopkins University
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Brandt, Jason (2018) https: //journals.lww.com/cogbehavneurol/fulltext/2001/10000/behavioral_changes_in_huntington_disease.4.aspx Behavioral Changes in Huntington Disease. Cogn Behav Neurol 31:26-35
Carlson, M C; Brandt, J; Steele, C et al. (2001) Predictor index of mortality in dementia patients upon entry into long-term care. J Gerontol A Biol Sci Med Sci 56:M567-70
Rich, J B; Campodonico, J R; Rothlind, J et al. (1997) Perseverations during paired-associate learning in Huntington's disease. J Clin Exp Neuropsychol 19:191-203
Barr, A; Brandt, J (1996) Word-list generation deficits in dementia. J Clin Exp Neuropsychol 18:810-22
Rich, J B; Bylsma, F W; Brandt, J (1996) Item priming and skill learning in amnesia. J Clin Exp Neuropsychol 18:148-58
Kraus, M F (1995) Neuropsychiatric sequelae of stroke and traumatic brain injury: the role of psychostimulants. Int J Psychiatry Med 25:39-51
Brandt, J; Bylsma, F W; Aylward, E H et al. (1995) Impaired source memory in Huntington's disease and its relation to basal ganglia atrophy. J Clin Exp Neuropsychol 17:868-77
Xeno Rasmusson, D; Brandt, J (1995) Instability of cognitive asymmetry in Alzheimer's disease. J Clin Exp Neuropsychol 17:449-58
Bylsma, F W; Peyser, C E; Folstein, S E et al. (1994) EEG power spectra in Huntington's disease: clinical and neuropsychological correlates. Neuropsychologia 32:137-50
Rasmusson, D X; Allen, J D (1994) Intertarget interval does not affect P300 within oddball series. Int J Psychophysiol 17:57-63

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