This proposal requests funding to continue a program for predoctoral training in the molecular basis of immunity and pathogenesis of infectious diseases. The training program is centered in the Department of Microbiology and Immunology of the Wake Forest University School of Medicine. This proposal seeks funding for 4 predoctoral positions per year for 5 years. The goal of the training program is to prepare trainees for careers in research and teaching. The training program in its present form was developed in 1985, when the Program Director, Dr. Steven Mizel, became the Departmental Chair. Training of predoctoral students consists of a program of coursework and research leading to a Ph.D. in Microbiology and Immunology. The training faculty consists of nine Departmental faculty and two faculty members who hold cross-appointments in the Department. The faculty includes established investigators in the fields of immunology, inflammation, bacteriology, virology, and viral and bacterial pathogenesis. Attractive features of the training program include: 1) experienced faculty with a high degree of extramural funding and a strong commitment to collaborative research; 2) extensive faculty participation in the training of each student; and 3) An intensive recruiting strategy that has been highly successful in the recruitment of under-represented minority students and has maintained the overall high quality of matriculating students. The success of the training program is evidenced by the very strong publication record of the trainees and the very high quality of their subsequent postdoctoral positions.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Institutional National Research Service Award (T32)
Project #
5T32AI007401-13
Application #
6743169
Study Section
Microbiology and Infectious Diseases B Subcommittee (MID)
Program Officer
Mcsweegan, Edward
Project Start
1991-09-01
Project End
2007-06-30
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
13
Fiscal Year
2004
Total Cost
$166,508
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
937727907
City
Winston-Salem
State
NC
Country
United States
Zip Code
27157
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Holbrook, Beth C; Kim, Jong R; Blevins, Lance K et al. (2016) A Novel R848-Conjugated Inactivated Influenza Virus Vaccine Is Efficacious and Safe in a Neonate Nonhuman Primate Model. J Immunol 197:555-64
McKay, Jerome T; Egan, Ryan P; Yammani, Rama D et al. (2015) PD-1 suppresses protective immunity to Streptococcus pneumoniae through a B cell-intrinsic mechanism. J Immunol 194:2289-99
Turner, Roberta L; Groitl, Peter; Dobner, Thomas et al. (2015) Adenovirus replaces mitotic checkpoint controls. J Virol 89:5083-96

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