While the scale of the HIV epidemic remains large, it has entered a promising new phase, marked by unprecedented progress and opportunities. In view of the need to rigorously test interventions to improve the uptake, implementation, and translation of recent scientific findings into standard of care (the know-do gap), as well as to evaluate the impact of bringing such interventions to scale, we propose to launch a new research training program focused on Global HIV Implementation Science. Implementation science is the scientific study of methods to promote integration of research findings and evidence-based interventions into health care policy and practice, thus improving the quality and effectiveness of health services. A key element of translational research, implementation science encompasses a broad range of skills, including epidemiology, biostatistics, health economics, decision science, and sociology. The goal of the proposed Training Program is to prepare well qualified individuals for careers as independently-funded researchers and for leadership in global HIV implementation research. We have assembled an outstanding group of diverse faculty from multiple schools, departments, and centers at Columbia University and abroad who have distinguished themselves in mentorship and are leading cutting edge implementation research addressing HIV prevention among key populations, linkage to and retention in care, prevention of mother to child transmission, and TB/HIV integration. The Training Program will encompass streamlined coursework based on an individualized training plan;weekly faculty-trainee seminars;tailored mentorship;research experience in a variety of domestic and international field settings;presentations;manuscript and grant preparation;research seminars and colloquia;and instruction in the responsible conduct of research. The Training Program will also include rigorous evaluation of the quality and effectiveness of the Training Program, to ensure that trainees achieve the competencies and skills necessary for success as future leaders in HIV implementation science research. The five-year program aims to support seven (three predoctoral and four postdoctoral) trainees at any one time. Among the postdoctoral trainees, a mix of trainees with PhD, DrPH, and MD degrees will be sought. Predoctoral trainees will be required to pursue a doctoral degree in Epidemiology. The period of support will be three years for predoctoral candidates and two years for postdoctoral candidates. With stellar faculty, a unique training environment, and unparalleled research opportunities in domestic and international field settings, we are well-poised to lead this novel effort and nurture new investigators trained in multidimensional, interdisciplinary approaches to advance scientific knowledge and demonstrate the impact of interventions.
Despite recent advances in prevention and treatment, the scale of the HIV epidemic remains large. The proposed research training program aims to increase the number of independent investigators with the knowledge and skills needed to rigorously test interventions to improve the uptake, implementation, and translation of recent scientific findings into standard of care (the know-do gap), as well as to evaluate the impact of bringing such interventions to scale. With stellar faculty, a unique training environment, and unparalleled research opportunities in domestic and international field settings, we are well-poised to lead this novel effort and nurture new investigators trained in multidimensional, interdisciplinary approaches to advance scientific knowledge and evaluate the impact of interventions which address this public health challenge.
|Tamir, Hod; Krupp, Karl; Stephens, Dionne P et al. (2018) Addressing Prevention Among HIV-Uninfected Women in PMTCT Programs in South India. J Assoc Nurses AIDS Care 29:45-52|
|Garnett, Matthew; Hirsch-Moverman, Yael; Franks, Julie et al. (2018) Limited awareness of pre-exposure prophylaxis among black men who have sex with men and transgender women in New York city. AIDS Care 30:9-17|
|Justman, Jessica E; Nair, Gonasagrie Lulu; Hendrix, Craig W et al. (2018) Pharmacokinetics and Pharmacodynamics of Tenofovir Reduced-Glycerin 1% Gel in the Rectal and Vaginal Compartments in Women: A Cross-Compartmental Study With Directly Observed Dosing. J Acquir Immune Defic Syndr 78:175-182|
|Palma, Anton M; Rabkin, Miriam; Simelane, Samkelo et al. (2018) A time-motion study of cardiovascular disease risk factor screening integrated into HIV clinic visits in Swaziland. J Int AIDS Soc 21:e25099|
|Soler, Jorge H; Caldwell, Cleopatra H; Córdova, David et al. (2018) Who counts as family? Family typologies, family support, and family undermining among young adult gay and bisexual men. Sex Res Social Policy 15:123-138|
|Sania, Ayesha; Smith, Emily R; Manji, Karim et al. (2018) Neonatal and Infant Mortality Risk Associated with Preterm and Small for Gestational Age Births in Tanzania: Individual Level Pooled Analysis Using the Intergrowth Standard. J Pediatr 192:66-72.e4|
|Hirshfield, Sabina; Teran, Richard A; Downing Jr, Martin J et al. (2018) Quantification of HIV-1 RNA Among Men Who Have Sex With Men Using an At-Home Self-Collected Dried Blood Spot Specimen: Feasibility Study. JMIR Public Health Surveill 4:e10847|
|Rabkin, Miriam; Palma, Anton; McNairy, Margaret L et al. (2018) Integrating cardiovascular disease risk factor screening into HIV services in Swaziland: lessons from an implementation science study. AIDS 32 Suppl 1:S43-S46|
|Thomann, Matthew; Grosso, Ashley; Zapata, Richard et al. (2018) 'WTF is PrEP?': attitudes towards pre-exposure prophylaxis among men who have sex with men and transgender women in New York City. Cult Health Sex 20:772-786|
|Franks, Julie; Mannheimer, Sharon B; Hirsch-Moverman, Yael et al. (2018) Multiple strategies to identify HIV-positive black men who have sex with men and transgender women in New York City: a cross-sectional analysis of recruitment results. J Int AIDS Soc 21:|
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