Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
5T32CA009579-04
Application #
3533624
Study Section
Cancer Institutional Fellowship Review Committee (CT)
Project Start
1987-05-01
Project End
1992-04-30
Budget Start
1990-05-01
Budget End
1991-04-30
Support Year
4
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Sanford-Burnham Medical Research Institute
Department
Type
DUNS #
009214214
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Komatsu, Masanobu; Ruoslahti, Erkki (2005) R-Ras is a global regulator of vascular regeneration that suppresses intimal hyperplasia and tumor angiogenesis. Nat Med 11:1346-50
Brown, Darren M; Ruoslahti, Erkki (2004) Metadherin, a cell surface protein in breast tumors that mediates lung metastasis. Cancer Cell 5:365-74
Majumdar, Mousumi; Vuori, Kristiina; Stallcup, William B (2003) Engagement of the NG2 proteoglycan triggers cell spreading via rac and p130cas. Cell Signal 15:79-84
Zou, June X; Liu, Yanqiu; Pasquale, Elena B et al. (2002) Activated SRC oncogene phosphorylates R-ras and suppresses integrin activity. J Biol Chem 277:1824-7
Abassi, Yama A; Vuori, Kristiina (2002) Tyrosine 221 in Crk regulates adhesion-dependent membrane localization of Crk and Rac and activation of Rac signaling. EMBO J 21:4571-82
Matter, M L; Ruoslahti, E (2001) A signaling pathway from the alpha5beta1 and alpha(v)beta3 integrins that elevates bcl-2 transcription. J Biol Chem 276:27757-63
Goretzki, L; Lombardo, C R; Stallcup, W B (2000) Binding of the NG2 proteoglycan to kringle domains modulates the functional properties of angiostatin and plasmin(ogen). J Biol Chem 275:28625-33
Zou, J X; Wang, B; Kalo, M S et al. (1999) An Eph receptor regulates integrin activity through R-Ras. Proc Natl Acad Sci U S A 96:13813-8
Niemeyer, C C; Persico, M G; Adamson, E D (1998) Cripto: roles in mammary cell growth, survival, differentiation and transformation. Cell Death Differ 5:440-9
Connor, R J; Menzel, P; Pasquale, E B (1998) Expression and tyrosine phosphorylation of Eph receptors suggest multiple mechanisms in patterning of the visual system. Dev Biol 193:21-35

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