The objective of this proposed Ohio State University (OSU) postdoctoral clinical T32 training program entitled: """"""""Training Hematology and Oncology Fellows in Clinical Research"""""""" is to provide a state of the art clinical research training experienc specifically for postdoctoral fellows in hematology and oncology with an M.D., D.O. or equivalent degree who have demonstrated a firm commitment to patient oriented cancer research. The overriding goal of this training program is to prepare Hematology and Oncology fellows in the OSU Divisions of Hematology and Medical Oncology for academic careers in clinical and translational cancer investigation. The rationale for this training program is based on our firm belief that progress in cancer therapy and prevention will require strong collaborative efforts, and that patient oriented physician investigators will provide a critical link with physician-scientists and basic scientists toward this goal. The OSU Comprehensive Cancer Center (OSU CCC) provides a rich research environment that fosters collaborations among multiple disciplines, yet which currently lacks a focused mentoring experience for physicians interested primarily in pursuing patient oriented cancer research. The recent explosive growth of scientific discoveries and the increasing complexity of cancer clinical trials particularly, phase I/II studie of novel therapeutic agents and regimens, make it imperative that trainees in hematology and oncology acquire the proper mentoring and training to prepare them for careers in clinical and translational investigation. This program recognizes that successful preparation of fellowship trainees for productive academic careers is dependent upon many factors including an intellectually rigorous curriculum, adequate mentoring and support from senior faculty, protected time for academic training during fellowship, """"""""hands on"""""""" experience in developing and writing clinical studies and research papers, and adequate opportunities to enhance their OSU experience with extramural programs and workshops sponsored by the NCI or other professional academic organizations such as ASCO and ASH. The participating members consist of the Program Directors, Coordinating Committee members, Advisory Committee members, primary mentors, and contributing faculty chosen based on their prior track record of successful mentoring as well as their demonstrated commitment to clinical and translational research. This program has a proposed duration of two years and will focus on the strengths of the OSU CCC, primarily in the fields of cancer prevention and experimental therapeutics. It is designed to foster and ensure the development of fellowship trainees who will be well prepared not only to assume positions as faculty members upon graduation but who will be empowered to become independent clinical and translational investigators in their own right. Furthermore, OSU is deeply committed to training women and members of underrepresented racial and ethnic groups for academic careers, and this program will build upon our proven success in recruiting and training female and underrepresented minority fellows.

Public Health Relevance

of this proposed training program to Public Health is that progress in cancer therapy and prevention will, we firmly believe, require strong collaborative efforts, and that well trained patient oriented physician investigators will provide critical link with physician-scientists and basic scientists in pursuit of this goal.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Institutional National Research Service Award (T32)
Project #
5T32CA165998-02
Application #
8520267
Study Section
Subcommittee G - Education (NCI)
Program Officer
Damico, Mark W
Project Start
2012-08-01
Project End
2017-07-31
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
2
Fiscal Year
2013
Total Cost
$196,169
Indirect Cost
$13,931
Name
Ohio State University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
832127323
City
Columbus
State
OH
Country
United States
Zip Code
43210
Wall, Sarah A; Zhao, Qiuhong; Yearsley, Martha et al. (2018) Complement-mediated thrombotic microangiopathy as a link between endothelial damage and steroid-refractory GVHD. Blood Adv 2:2619-2628
Calzada, Oscar; Switchenko, Jeffrey M; Maly, Joseph J et al. (2018) Deferred treatment is a safe and viable option for selected patients with mantle cell lymphoma. Leuk Lymphoma :1-9
Dugan, James P; Haverkos, Bradley M; Villagomez, Lynda et al. (2018) Complete and Durable Responses in Primary Central Nervous System Posttransplant Lymphoproliferative Disorder with Zidovudine, Ganciclovir, Rituximab, and Dexamethasone. Clin Cancer Res 24:3273-3281
Greenwell, I Brian; Staton, Ashley D; Lee, Michael J et al. (2018) Complex karyotype in patients with mantle cell lymphoma predicts inferior survival and poor response to intensive induction therapy. Cancer 124:2306-2315
Bupathi, Manojkumar; Ahn, Daniel H; Bekaii-Saab, Tanios (2017) Therapeutic options for intrahepatic cholangiocarcinoma. Hepatobiliary Surg Nutr 6:91-100
Haverkos, B M; Huang, Y; Elder, P et al. (2017) A single center's experience using four different front line mobilization strategies in lymphoma patients planned to undergo autologous hematopoietic cell transplantation. Bone Marrow Transplant 52:561-566
Ahn, Daniel H; Wu, Christina; Wei, Lai et al. (2017) The Efficacy of Adjuvant Chemotherapy in Patients With Stage II/III Resected Rectal Cancer Treated With Neoadjuvant Chemoradiation Therapy. Am J Clin Oncol 40:531-534
Sborov, Douglas W; Canella, Alessandro; Hade, Erinn M et al. (2017) A phase 1 trial of the HDAC inhibitor AR-42 in patients with multiple myeloma and T- and B-cell lymphomas. Leuk Lymphoma 58:2310-2318
Landsburg, Daniel J; Falkiewicz, Marissa K; Maly, Joseph et al. (2017) Outcomes of Patients With Double-Hit Lymphoma Who Achieve First Complete Remission. J Clin Oncol 35:2260-2267
Maly, Joseph J; Christian, Beth A; Zhu, Xiaohua et al. (2017) A Phase I/II Trial of Panobinostat in Combination With Lenalidomide in Patients With Relapsed or Refractory Hodgkin Lymphoma. Clin Lymphoma Myeloma Leuk 17:347-353

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