EXCEED THE SPACE PROVIDED. The overall goal of the Nephrology Training Program at Massachusetts General Hospital is to develop highly committed MDs and/or PhDs into mature, broadly educated and independent scientists who will pursue research careers in academic nephrology. The major component of this renewed program is the training of eight postdoctoral fellows annually in the conduct of basic or clinical-based research, under supervision of established investigators serving as mentors, in well-equipped research facilities supported by state-of-the-art core services. Bench work is complemented by didactic instruction and enrichment activities. Intensive training in basic or clinical research is provided by senior and junior faculty preceptors, in a multidisciplinary environment conducive of collaborative interactions among groups. There are ample opportunities for training in several disciplines including membrane biology, biophysics, genetics, genomics, immunology, transplantation biology, inflammation, kidney development, biochemistry, cell signaling, structural biology and outcomes and epidemiology research. These disciplines are applied to nine research themes central to the study of kidney disease. These approaches are applied in many cases to clinically relevant diseases such as nephritis, acute renal failure, electrolyte disorders, polycystic kidney disease, bioincompatibility, allograft rejection, vasculitis and progressive renal dysfunction. Didactic instruction through courses and weekly lectures offered at Massachusetts General Hospital, Harvard Medical School, Harvard School of Public Health or Harvard College complements bench training. Courses in biostatistics, epidemiology, clinical effectiveness and outcomes research are offered for fellows pursuing careers in clinical investigation. All research trainees are required to participate in an annual course in the responsible conduct of research. A recently established Society of Fellows at Massachusetts General Hospital serves to introduce fellows to each other, and offers lectures on grant writing, bioethics, conflict resolution, job hunting, and time management in two career families. PERFORMANCE SITE ========================================Section End===========================================

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
5T32DK007540-20
Application #
6919844
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Program Officer
Rankin, Tracy L
Project Start
1986-07-01
Project End
2006-06-30
Budget Start
2005-07-01
Budget End
2006-06-30
Support Year
20
Fiscal Year
2005
Total Cost
$425,968
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199
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Cortazar, Frank B; Pendergraft 3rd, William F; Wenger, Julia et al. (2017) Effect of Continuous B Cell Depletion With Rituximab on Pathogenic Autoantibodies and Total IgG Levels in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol 69:1045-1053
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