Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Institutional National Research Service Award (T32)
Project #
1T32DK007667-01A2
Application #
2135262
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1994-09-30
Project End
1999-08-31
Budget Start
1994-09-30
Budget End
1995-08-31
Support Year
1
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Florida
Department
Type
Organized Research Units
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Lima, Carolina P; Davis, Steven R; Mackey, Amy D et al. (2006) Vitamin B-6 deficiency suppresses the hepatic transsulfuration pathway but increases glutathione concentration in rats fed AIN-76A or AIN-93G diets. J Nutr 136:2141-7
Scheer, Jennifer B; Mackey, Amy D; Gregory 3rd, Jesse F (2005) Activities of hepatic cytosolic and mitochondrial forms of serine hydroxymethyltransferase and hepatic glycine concentration are affected by vitamin B-6 intake in rats. J Nutr 135:233-8
Mackey, Amy D; McMahon, Robert J; Townsend, Justin H et al. (2004) Uptake, hydrolysis, and metabolism of pyridoxine-5'-beta-D-glucoside in Caco-2 cells. J Nutr 134:842-6
Mackey, Amy D; Lieu, Siam O; Carman, Catherine et al. (2003) Hydrolytic activity toward pyridoxine-5'-beta-D-glucoside in rat intestinal mucosa is not increased by vitamin B-6 deficiency: effect of basal diet composition and pyridoxine intake. J Nutr 133:1362-7
Mackey, Amy D; Henderson, George N; Gregory 3rd, Jesse F (2002) Enzymatic hydrolysis of pyridoxine-5'-beta-D-glucoside is catalyzed by intestinal lactase-phlorizin hydrolase. J Biol Chem 277:26858-64
Armada, Linda J; Mackey, Amy D; Gregory 3rd, Jesse F (2002) Intestinal brush border membrane catalyzes hydrolysis of pyridoxine-5'-beta-D-glucoside and exhibits parallel developmental changes of hydrolytic activities toward pyridoxine-5'-beta-D-glucoside and lactose in rats. J Nutr 132:2695-9
Cousins, R J; McMahon, R J (2000) Integrative aspects of zinc transporters. J Nutr 130:1384S-7S
Boddie, A M; Dedlow, E R; Nackashi, J A et al. (2000) Folate absorption in women with a history of neural tube defect-affected pregnancy. Am J Clin Nutr 72:154-8
Blanchard, R K; Cousins, R J (2000) Regulation of intestinal gene expression by dietary zinc: induction of uroguanylin mRNA by zinc deficiency. J Nutr 130:1393S-8S
Davis, B A; Blanchard, R K; Lanningham-Foster, L et al. (1998) Structural characterization of the rat cysteine-rich intestinal protein gene and overexpression of this LIM-only protein in transgenic mice. DNA Cell Biol 17:1057-64

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