The objective of the Toxicology Training Program at the University of Rochester is to provide quality per- and postdoctoral training in toxicology. The training is highly interdisciplinary. Many of the twenty-eight participating faculty participating are associated with the University's NIEHS-funded Environmental Health Sciences Center. The program faculty hold primary appointments in the Departments of Biochemistry & Biophysics, Biology, Environmental Medicine, Microbiology & Immunology, Medicine, Neurobiology & Anatomy, Obstetrics & Gynecology, Pathology, Pediatrics, Pharmacology & Physiology, and Radiation Oncology, Medicine, Neurobiology & Oncology. There are six major training areas: Cellular & Molecular Toxicology, Carcinogenesis, Immunotoxicology, Neurotoxicology, Pulmonary Toxicology, and Reproductive & Developmental Toxicology. Trainees are selected on the basis of undergraduate records, letters of recommendation, standardized test scores, and personal interviews. Most of these individuals have undergraduate or Master's degrees in Chemistry, Biochemistry, Biology, Toxicology or related Biological Sciences. Funds are requested to provide sixty months of support for each of eighteen predoctoral trainees. The major emphasis of the program is on research. This emphasis and the rich research environment provides students the training needed so that they can successfully carry out independent, but interactive, research programs. Didactic courses and seminars complement the research to prepare students for the variety of career opportunities available in toxicology. Funding is requested to provide support for twenty-four months for each of four postdoctoral trainees per year. Performance of research encompassing the practices and principles of toxicology is the primary activity of postdoctoral fellows. They also participate in the toxicology core course presented to all predoctoral trainees as well as in seminars. Traditionally, most of these trainees have Ph.D. degrees. However, an M.D. with specific interests in basic research in Occupational/Environmental Medicine will occasionally be supported. Funds are also requested for three medical students per year for three months during the summer in disciplines related to Environmental and Occupational Medicine. The Toxicology Training Program is administered by the Program director in conjunction with the administrative structure of the University's Environmental Health Sciences Center and the Department of Environmental Medicine.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Institutional National Research Service Award (T32)
Project #
5T32ES007026-23
Application #
6150678
Study Section
Environmental Health Sciences Review Committee (EHS)
Program Officer
Shreffler, Carol K
Project Start
1978-07-01
Project End
2003-06-30
Budget Start
2000-07-01
Budget End
2001-06-30
Support Year
23
Fiscal Year
2000
Total Cost
$633,034
Indirect Cost
Name
University of Rochester
Department
Public Health & Prev Medicine
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Klocke, Carolyn; Allen, Joshua L; Sobolewski, Marissa et al. (2018) Exposure to fine and ultrafine particulate matter during gestation alters postnatal oligodendrocyte maturation, proliferation capacity, and myelination. Neurotoxicology 65:196-206
Stowell, Rianne D; Wong, Elissa L; Batchelor, Hanna N et al. (2018) Cerebellar microglia are dynamically unique and survey Purkinje neurons in vivo. Dev Neurobiol 78:627-644
Duffney, Parker F; Falsetta, Megan L; Rackow, Ashley R et al. (2018) Key roles for lipid mediators in the adaptive immune response. J Clin Invest 128:2724-2731
Morris-Schaffer, Keith; Sobolewski, Marissa; Allen, Joshua L et al. (2018) Effect of neonatal hyperoxia followed by concentrated ambient ultrafine particle exposure on cumulative learning in C57Bl/6J mice. Neurotoxicology 67:234-244
Boule, Lisbeth A; Burke, Catherine G; Jin, Guang-Bi et al. (2018) Aryl hydrocarbon receptor signaling modulates antiviral immune responses: ligand metabolism rather than chemical source is the stronger predictor of outcome. Sci Rep 8:1826
Sobolewski, Marissa; Varma, Garima; Adams, Beth et al. (2018) Developmental Lead Exposure and Prenatal Stress Result in Sex-Specific Reprograming of Adult Stress Physiology and Epigenetic Profiles in Brain. Toxicol Sci 163:478-489
Begolly, Sage; Olschowka, John A; Love, Tanzy et al. (2018) Fractionation enhances acute oligodendrocyte progenitor cell radiation sensitivity and leads to long term depletion. Glia 66:846-861
Wong, Elissa L; Lutz, Nina M; Hogan, Victoria A et al. (2018) Developmental alcohol exposure impairs synaptic plasticity without overtly altering microglial function in mouse visual cortex. Brain Behav Immun 67:257-278
Franchini, Anthony M; Lawrence, B Paige (2018) Environmental exposures are hidden modifiers of anti-viral immunity. Curr Opin Toxicol 10:54-59
Beach, Tyler A; Groves, Angela M; Johnston, Carl J et al. (2018) Recurrent DNA damage is associated with persistent injury in progressive radiation-induced pulmonary fibrosis. Int J Radiat Biol 94:1104-1115

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