Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Institutional National Research Service Award (T32)
Project #
5T32ES007045-10
Application #
3535972
Study Section
Environmental Health Sciences Review Committee (EHS)
Project Start
1977-07-01
Project End
1988-06-30
Budget Start
1987-07-01
Budget End
1988-06-30
Support Year
10
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Mississippi Medical Center
Department
Type
Schools of Medicine
DUNS #
928824473
City
Jackson
State
MS
Country
United States
Zip Code
39216
Abdul-Hussain, S K; Mehendale, H M (1992) Ongoing hepatocellular regeneration and resiliency toward galactosamine hepatotoxicity. Arch Toxicol 66:729-42
Abdul-Hussain, S K; Mehendale, H M (1991) Studies on the age-dependent effects of galactosamine in primary rat hepatocyte cultures. Toxicol Appl Pharmacol 107:504-13
Faroon, O M; Henry, R W; Soni, M G et al. (1991) Potentiation of BrCCl3 hepatotoxicity by chlordecone: biochemical and ultrastructural study. Toxicol Appl Pharmacol 110:185-97
Utley, W S; Mehendale, H M (1991) Evidence for stimulated glutathione synthesis by phenobarbital pretreatment during an oxidative challenge in isolated hepatocytes. J Biochem Toxicol 6:101-13
Utley, W S; Mehendale, H M (1990) Phenobarbital-induced cytoprotective mechanisms in menadione metabolism: the role of glutathione reductase and DT-diaphorase. Int J Biochem 22:957-67
Mehendale, H M (1990) Potentiation of halomethane hepatotoxicity by chlordecone: a hypothesis for the mechanism. Med Hypotheses 33:289-99
Faroon, O M; Mehendale, H M (1990) Bromotrichloromethane hepatotoxicity. The role of stimulated hepatocellular regeneration in recovery: biochemical and histopathological studies in control and chlordecone pretreated male rats. Toxicol Pathol 18:667-77
Utley, W S; Mehendale, H M (1989) Phenobarbital-induced cytosolic cytoprotective mechanisms that offset increases in NADPH cytochrome P450 reductase activity in menadione-mediated cytotoxicity. Toxicol Appl Pharmacol 99:323-33
Young, R A; Mehendale, H M (1989) Effects of short-term and long-term administration of amiodarone on hepatobiliary function in male rats. J Appl Toxicol 9:407-12
Kodavanti, P R; Joshi, U M; Young, R A et al. (1989) Protection of hepatotoxic and lethal effects of CCl4 by partial hepatectomy. Toxicol Pathol 17:494-505

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