Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Institutional National Research Service Award (T32)
Project #
5T32ES007284-02
Application #
2156613
Study Section
Special Emphasis Panel (SRC (T))
Project Start
1995-07-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Pathology
Type
Schools of Dentistry
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Peariso, Katrina; Huffman, David L; Penner-Hahn, James E et al. (2003) The PcoC copper resistance protein coordinates Cu(I) via novel S-methionine interactions. J Am Chem Soc 125:342-3
Huffman, David L; Huyett, Jennifer; Outten, F Wayne et al. (2002) Spectroscopy of Cu(II)-PcoC and the multicopper oxidase function of PcoA, two essential components of Escherichia coli pco copper resistance operon. Biochemistry 41:10046-55
Torres, A S; Petri, V; Rae, T D et al. (2001) Copper stabilizes a heterodimer of the yCCS metallochaperone and its target superoxide dismutase. J Biol Chem 276:38410-6
Outten, F W; Huffman, D L; Hale, J A et al. (2001) The independent cue and cus systems confer copper tolerance during aerobic and anaerobic growth in Escherichia coli. J Biol Chem 276:30670-7
Caselli, E; Powers, R A; Blasczcak, L C et al. (2001) Energetic, structural, and antimicrobial analyses of beta-lactam side chain recognition by beta-lactamases. Chem Biol 8:17-31
Banci, L; Bertini, I; Ciofi-Baffoni, S et al. (2001) Solution structure of the yeast copper transporter domain Ccc2a in the apo and Cu(I)-loaded states. J Biol Chem 276:8415-26
Huffman, D L; O'Halloran, T V (2000) Energetics of copper trafficking between the Atx1 metallochaperone and the intracellular copper transporter, Ccc2. J Biol Chem 275:18611-4
Powers, R A; Blazquez, J; Weston, G S et al. (1999) The complexed structure and antimicrobial activity of a non-beta-lactam inhibitor of AmpC beta-lactamase. Protein Sci 8:2330-7
Norvell, S M; Green, K J (1998) Contributions of extracellular and intracellular domains of full length and chimeric cadherin molecules to junction assembly in epithelial cells. J Cell Sci 111 ( Pt 9):1305-18