Abstract

EXCEED THESPACE PROVIDED. Seventeen scientists from the Oregon Health Sciences University are seeking renewal of a Dredoctoral training grant to attract outstanding graduate students toward careers inophthalmic -esearch. Funding for 1 predoctoral students annuallyis requested. A uniquefeature of this ipplication is the selection of students who are presently performing research outside of ophthalmology. Students are encouraged to pursue ophthalmicscience by repeated emphasis on he opportunities in eye-related research. The quality of the institution, the talents of the specific faculty, the abilities of the applicant pool, and the proven success of the program areadditional strengths of this application. PERFORMANCE SITE(S) (organization, city, state) Oregon Health Sciences University Casey Eye Institute 3181 S.W.Sam Jackson Park Rd. 3375 S.W. Terwilliger Blvd Portland, OR 97201-3098 Portland, OR 07201-4197 KEY PERSONNEL. See instructions on Page 11. Use continuation pages as neededo provide the required information in the format shown below. Name Organization Role on Project James T. Rosenbaum, M.D. Casey Eye Institute P.I. Ted Acott, Ph.D. Casey Eye Institute Preceptor Brian Druker, M.D. Oregon Health Sciences Univ. Preceptor David Farrens, Ph.D. Oregon Health Sciences Univ. Preceptor, Ann Hill, Ph.D. Oregon Health Sciences Univ. Preceptor David C. Johnson, Ph.D. Oregon Health Sciences Univ. Preceptor Hua Lu, Ph.D. Oregon Health Sciences Univ, Preceptor Bruce'E. Magun, Ph.D. Oregon Health Sciences Univ, Preceptor Linda Musil, Ph.D. Oregon Health Sciences Univ. Preceptor Jay Nelson, Ph.D. Oregon Health Sciences Univ. Preceptor Tammy Martin, Ph.D. Casey Eye Institute Preceptor Edward Neuwelt, M.D. Oregon Health Sciences Univ. Preceptor Kim A. Neve, Ph.D. Oregon Health Sciences Univ, Preceptor David C. Parker, Ph.D. Oregon Health Sciences Univ Preceptor PUS 398 (Rev. 4/98) Page 2 BB Number pages consecutively at tho bottom throughout (ho application OonoJ use suffixes such as 3a. 'lh ========================================Section End===========================================

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Institutional National Research Service Award (T32)
Project #
5T32EY007123-15
Application #
6950385
Study Section
Special Emphasis Panel (ZEY1-VSN (01))
Program Officer
Hunter, Chyren
Project Start
1991-09-30
Project End
2008-01-31
Budget Start
2005-09-30
Budget End
2008-01-31
Support Year
15
Fiscal Year
2005
Total Cost
$259,473
Indirect Cost

  Institution

Name
Oregon Health and Science University
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
096997515
City
Portland
State
OR
Country
United States
Zip Code
97239

  Publications

Lang, Anna; Brien, James D; Messaoudi, Ilhem et al. (2008) Age-related dysregulation of CD8+ T cell memory specific for a persistent virus is independent of viral replication. J Immunol 180:4848-57
Thauland, Timothy J; Koguchi, Yoshinobu; Wetzel, Scott A et al. (2008) Th1 and Th2 cells form morphologically distinct immunological synapses. J Immunol 181:393-9
Kelly, Sean M; Vanslyke, Judy K; Musil, Linda S (2007) Regulation of ubiquitin-proteasome system mediated degradation by cytosolic stress. Mol Biol Cell 18:4279-91
Rosenzweig, Holly L; Minami, Manabu; Lessov, Nikola S et al. (2007) Endotoxin preconditioning protects against the cytotoxic effects of TNFalpha after stroke: a novel role for TNFalpha in LPS-ischemic tolerance. J Cereb Blood Flow Metab 27:1663-74
Davey, Michael P; Martin, Tammy M; Planck, Stephen R et al. (2006) Human endothelial cells express NOD2/CARD15 and increase IL-6 secretion in response to muramyl dipeptide. Microvasc Res 71:103-7
Silverman, Matthew D; Babra, Bobby; Pan, Yuzhen et al. (2005) Differential E-selectin expression by iris versus retina microvascular endothelial cells cultured from the same individuals. Microvasc Res 70:32-42
Gaston, Isabelle; Johnson, Kara J; Oda, Tsukasa et al. (2004) Coexistence of phosphotyrosine-dependent and -independent interactions between Cbl and Bcr-Abl. Exp Hematol 32:113-21
Rosenzweig, Holly L; Lessov, Nikola S; Henshall, David C et al. (2004) Endotoxin preconditioning prevents cellular inflammatory response during ischemic neuroprotection in mice. Stroke 35:2576-81
Janz, Jay M; Farrens, David L (2004) Rhodopsin activation exposes a key hydrophobic binding site for the transducin alpha-subunit C terminus. J Biol Chem 279:29767-73
Janz, Jay M; Farrens, David L (2004) Role of the retinal hydrogen bond network in rhodopsin Schiff base stability and hydrolysis. J Biol Chem 279:55886-94

Showing the most recent 10 out of 27 publications