The aim of this program is to educate well-trained scholars with an advanced appreciation of genetic rationales and methods to 1) perform basic and applied biomedical research, 2) provide future educators in this discipline, and 3) fulfill health- related positions, both academic and in industry, requiring a sophisticated understanding of genetics and genomics. The training faculty is comprised of fifty-five distinguished and respected members of the scientific community. Their specific strengths are focused in the areas of: chromosome organization and behavior, gene expression and developmental genetics, genetics of model organisms, population and evolutionary genetics, systems biology, and the genetics of human diseases with special emphasis on genetic alterations in cancer, diabetes, cardiac disorders and asthma. Diverse systems including viruses, bacteria, Arabidopsis, yeast, ciliates, Drosophila, nematodes, zebrafish, mice, humans, and a variety of other plant and animal species. Research is also characterized by the use of interdisciplinary approaches.

Public Health Relevance

The aim of this program is to educate well-trained scholars with an advanced appreciation of genetic rationales and methods to 1) perform basic and applied biomedical research, 2) provide future educators in this discipline, and 3) fulfill health- related positions, both academic and in industry, requiring a sophisticated understanding of genetics and genomics.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007197-38
Application #
8286880
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Haynes, Susan R
Project Start
1975-07-01
Project End
2016-06-30
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
38
Fiscal Year
2012
Total Cost
$803,782
Indirect Cost
$38,206
Name
University of Chicago
Department
Genetics
Type
Schools of Medicine
DUNS #
005421136
City
Chicago
State
IL
Country
United States
Zip Code
60637
Michaux, Jonathan B; Robin, François B; McFadden, William M et al. (2018) Excitable RhoA dynamics drive pulsed contractions in the early C. elegans embryo. J Cell Biol 217:4230-4252
Gonzales, Natalia M; Seo, Jungkyun; Hernandez Cordero, Ana I et al. (2018) Genome wide association analysis in a mouse advanced intercross line. Nat Commun 9:5162
Pavlovic, Bryan J; Blake, Lauren E; Roux, Julien et al. (2018) A Comparative Assessment of Human and Chimpanzee iPSC-derived Cardiomyocytes with Primary Heart Tissues. Sci Rep 8:15312
Smith, Joel; Coop, Graham; Stephens, Matthew et al. (2018) Estimating Time to the Common Ancestor for a Beneficial Allele. Mol Biol Evol 35:1003-1017
Steimle, Jeffrey D; Rankin, Scott A; Slagle, Christopher E et al. (2018) Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development. Proc Natl Acad Sci U S A 115:E10615-E10624
Blake, Lauren E; Thomas, Samantha M; Blischak, John D et al. (2018) A comparative study of endoderm differentiation in humans and chimpanzees. Genome Biol 19:162
Hernandez, Sonia L; Nelson, Mildred; Sampedro, Georgia R et al. (2018) Staphylococcus aureus alpha toxin activates Notch in vascular cells. Angiogenesis :
Chiang, Charleston W K; Marcus, Joseph H; Sidore, Carlo et al. (2018) Genomic history of the Sardinian population. Nat Genet 50:1426-1434
Mika, Katelyn M; Li, Xilong; DeMayo, Francesco J et al. (2018) An Ancient Fecundability-Associated Polymorphism Creates a GATA2 Binding Site in a Distal Enhancer of HLA-F. Am J Hum Genet 103:509-521
VanKuren, Nicholas W; Long, Manyuan (2018) Gene duplicates resolving sexual conflict rapidly evolved essential gametogenesis functions. Nat Ecol Evol 2:705-712

Showing the most recent 10 out of 178 publications