The Graduate Training Program in Molecular and Cellular Pharmacology at Stony Brook University trains Ph.D. students in the broad area of cell and molecular biology for careers in academia, government and industry. The Program is based in the Department of Pharmacological Sciences in the School of Medicine at SUNY-Stony Brook, but has an interdepartmental faculty including 64 potential mentors, 35 of whom are from other University Departments or the nearby Cold Spring Harbor Laboratory and Brookhaven National Laboratories. Students take courses in biochemistry, computational and cell biology, physiology and molecular genetics in the first year, with pharmacology and elective courses in the second year. The curriculum includes advanced courses in Neuropharmacology (including signal transduction), in Drug Design and DNA Damage, Repair and Carcinogenesis. Faculty members have been recruited to the Training Program to strengthen these areas. The training environment includes an active seminar series and participation in research symposia and minicourses. Training also involves experience teaching in courses offered to undergraduate majors in pharmacology. First year students participate in three laboratory rotations to prepare them to undertake dissertation research in any of the laboratories of the Training Program Faculty. The Training Program has trained 119 Ph.D. students in its 37-year history, and has 31 current trainees. The presence of seven underrepresented minority and 2 underprivileged students in the Program attests to a successful effort to recruit minority applicants.

Public Health Relevance

The Molecular and Cellular Pharmacology training program provides graduate students with a solid background in the discipline of Pharmacology by bringing together training faculty from different research fields involved in the discovery, development and use of therapeutic compounds, offering courses both in the basic principles and systems pharmacology and by providing opportunities to the students to present their research in national and international meetings. The training grant supports the students early during their training (1st and sometimes 2nd year), aids in the recruitment and retention of diverse students and supports training in responsible conduct in research.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007518-37
Application #
8495340
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Okita, Richard T
Project Start
1977-07-01
Project End
2017-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
37
Fiscal Year
2013
Total Cost
$291,884
Indirect Cost
$16,980
Name
State University New York Stony Brook
Department
Pharmacology
Type
Schools of Medicine
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794
Miyauchi, Jeremy Tetsuo; Caponegro, Michael D; Chen, Danling et al. (2018) Deletion of Neuropilin 1 from Microglia or Bone Marrow-Derived Macrophages Slows Glioma Progression. Cancer Res 78:685-694
Thompson, Kaitlyn K; Nissen, Jillian C; Pretory, Amanda et al. (2018) Tuftsin Combines With Remyelinating Therapy and Improves Outcomes in Models of CNS Demyelinating Disease. Front Immunol 9:2784
Miyauchi, Jeremy Tetsuo; Tsirka, Stella E (2018) Advances in immunotherapeutic research for glioma therapy. J Neurol 265:741-756
Amin, Johansen B; Leng, Xiaoling; Gochman, Aaron et al. (2018) A conserved glycine harboring disease-associated mutations permits NMDA receptor slow deactivation and high Ca2+ permeability. Nat Commun 9:3748
Amin, Johansen B; Wollmuth, Lonnie P (2018) A Swiss army knife for targeting receptors. Elife 7:
Kirschen, Gregory W; Kéry, Rachel; Liu, Hanxiao et al. (2018) Genetic dissection of the neuro-glio-vascular machinery in the adult brain. Mol Brain 11:2
Nissen, Jillian C; Thompson, Kaitlyn K; West, Brian L et al. (2018) Csf1R inhibition attenuates experimental autoimmune encephalomyelitis and promotes recovery. Exp Neurol 307:24-36
Caponegro, Michael D; Moffitt, Richard A; Tsirka, Stella E (2018) Expression of neuropilin-1 is linked to glioma associated microglia and macrophages and correlates with unfavorable prognosis in high grade gliomas. Oncotarget 9:35655-35665
Pulkoski-Gross, Michael J; Uys, Joachim D; Orr-Gandy, K Alexa et al. (2017) Novel sphingosine kinase-1 inhibitor, LCL351, reduces immune responses in murine DSS-induced colitis. Prostaglandins Other Lipid Mediat 130:47-56
Kirschen, Gregory W; Shen, Jia; Tian, Mu et al. (2017) Active Dentate Granule Cells Encode Experience to Promote the Addition of Adult-Born Hippocampal Neurons. J Neurosci 37:4661-4678

Showing the most recent 10 out of 78 publications