Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM007767-12
Application #
3537877
Study Section
Pharmacology-Toxicology Review Committee (PTR)
Project Start
1978-07-01
Project End
1993-06-30
Budget Start
1989-07-01
Budget End
1990-06-30
Support Year
12
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Hu, Yongjun; Epling, Daniel; Shi, Jian et al. (2018) Effect of biphenyl hydrolase-like (BPHL) gene disruption on the intestinal stability, permeability and absorption of valacyclovir in wildtype and Bphl knockout mice. Biochem Pharmacol 156:147-156
Kuai, Rui; Sun, Xiaoqi; Yuan, Wenmin et al. (2018) Dual TLR agonist nanodiscs as a strong adjuvant system for vaccines and immunotherapy. J Control Release 282:131-139
Livingston, Kathryn E; Mahoney, Jacob P; Manglik, Aashish et al. (2018) Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor. Elife 7:
Masureel, Matthieu; Zou, Yaozhong; Picard, Louis-Philippe et al. (2018) Structural insights into binding specificity, efficacy and bias of a ?2AR partial agonist. Nat Chem Biol 14:1059-1066
Sanchez, Jaquelyn N; Wang, Ton; Cohen, Mark S (2018) BRAF and MEK Inhibitors: Use and Resistance in BRAF-Mutated Cancers. Drugs 78:549-566
Epling, Daniel; Hu, Yongjun; Smith, David E (2018) Evaluating the intestinal and oral absorption of the prodrug valacyclovir in wildtype and huPepT1 transgenic mice. Biochem Pharmacol 155:1-7
Drake, Lindsey R; Scott, Peter J H (2018) DARK Classics in Chemical Neuroscience: Cocaine. ACS Chem Neurosci 9:2358-2372
Lamberts, Jennifer T; Rosenthal, Lisa D; Jutkiewicz, Emily M et al. (2018) Role of the guanine nucleotide binding protein, G?o, in the development of morphine tolerance and dependence. Psychopharmacology (Berl) 235:71-82
Beyett, Tyler S; Gan, Xinmin; Reilly, Shannon M et al. (2018) Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKK? for the treatment of obesity. Bioorg Med Chem 26:5443-5461
Senese, Nicolas B; Oginsky, Max; Neubig, Richard R et al. (2018) Role of hippocampal 5-HT1A receptors in the antidepressant-like phenotype of mice expressing RGS-insensitive G?i2 protein. Neuropharmacology 141:296-304

Showing the most recent 10 out of 325 publications