The Cellular Biotechnology Training Program (CBTP) at the University of Michigan seeks to prepare graduate students for scientific careers that will transform human health through biotechnological innovation. For over 25 years, CBTP has immersed students from diverse scientific disciplines in interdisciplinary training related to biotechnology in order to prepare the next generation of leaders for a variety of careers options, with an emphasis on opportunities outside of traditional academia. CBTP trainees belong to one of 9 graduate Ph.D. programs from four colleges at the university, including: Biological Chemistry, Biomedical Engineering, Chemical Engineering, Chemistry, Cellular and Developmental Biology, Medicinal Chemistry, Microbiology and Immunology, Molecular, Cellular and Developmental Biology, and Pharmaceutical Sciences. The training faculty are accomplished scientists and innovators who are dedicated to graduate education and mentorship. The unique programmatic activities of CBTP provide students with insights into experimental paradigms of diverse disciplines related to biotechnology, as well as exposure to concepts and practical aspects of entrepreneurship and commercialization. These activities include: (1) A biotechnology core course to provide background information on the field and require students to work in multi-disciplinary groups to generate biotechnological product ideas; (2) A required course in Research Responsibility and Ethics (PIBS503); (3) Monthly student dinner meetings to provide informal opportunities for presentation and discussion of student research projects; (4) Research internships in the biotechnology industry; (5) An Annual Symposium with an external keynote speaker and posters presented by students, faculty and affiliated biotechnology companies; (6) Mentoring lunches and networking opportunities with scientists and business leaders in local biotech companies; (7) A shadow program at the University of Michigan Technology Transfer Office and an affiliation with the CoE Center for Entrepreneurship to provide practical experience for our students in technology development into commercial products; and (8) Trainee evaluation and mentoring, and the use of individual development (IDPs) plans to promote career advancement. These innovative activities are a mechanism for student interaction and networking with peers, faculty and industry professionals and a centerpiece of CBTP. The strength of CBTP has been recognized by the University through significant financial support and by its designation as a certificate-granting program. Overall, CBTP reinforces the excellent academic education provided by departmental faculty by emphasizing interdisciplinary science and providing the tools to translate basic scientific knowledge into commercialized biotechnologies.

Public Health Relevance

The Cellular Biotechnology Training Program at the University of Michigan reaches across traditional academic boundaries to provide graduate students from a variety of scientific backgrounds with multidisciplinary training related to biotechnology and guidance about a wide- range of scientific career options. Our goal is to train future leaders who can transform human health through biotechnological innovation.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
2T32GM008353-26
Application #
9280027
Study Section
NIGMS Initial Review Group (TWD)
Program Officer
Brown, Patrick
Project Start
1991-07-01
Project End
2022-06-30
Budget Start
2017-07-01
Budget End
2018-06-30
Support Year
26
Fiscal Year
2017
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Youngblood, Richard L; Truong, Norman F; Segura, Tatiana et al. (2018) It's All in the Delivery: Designing Hydrogels for Cell and Non-viral Gene Therapies. Mol Ther 26:2087-2106
Li, Dan; Fawaz, Maria V; Morin, Emily E et al. (2018) Effect of Synthetic High Density Lipoproteins Modification with Polyethylene Glycol on Pharmacokinetics and Pharmacodynamics. Mol Pharm 15:83-96
Skiba, Meredith A; Sikkema, Andrew P; Moss, Nathan A et al. (2018) Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module. ACS Chem Biol 13:1640-1650
Chun, Stephanie W; Hinze, Meagan E; Skiba, Meredith A et al. (2018) Chemistry of a Unique Polyketide-like Synthase. J Am Chem Soc 140:2430-2433
Lesher-Pérez, Sasha Cai; Zhang, Chao; Takayama, Shuichi (2018) Capacitive coupling synchronizes autonomous microfluidic oscillators. Electrophoresis 39:1096-1103
Guo, Yanhong; Yuan, Wenmin; Yu, Bilian et al. (2018) Synthetic High-Density Lipoprotein-Mediated Targeted Delivery of Liver X Receptors Agonist Promotes Atherosclerosis Regression. EBioMedicine 28:225-233
Bezenah, Jonathan R; Kong, Yen P; Putnam, Andrew J (2018) Evaluating the potential of endothelial cells derived from human induced pluripotent stem cells to form microvascular networks in 3D cultures. Sci Rep 8:2671
Libiad, Marouane; Motl, Nicole; Akey, David L et al. (2018) Thiosulfate sulfurtransferase-like domain-containing 1 protein interacts with thioredoxin. J Biol Chem 293:2675-2686
Tay, Jia-Hui; Argüelles, Alonso J; DeMars 2nd, Matthew D et al. (2017) Regiodivergent Glycosylations of 6-Deoxy-erythronolide B and Oleandomycin-Derived Macrolactones Enabled by Chiral Acid Catalysis. J Am Chem Soc 139:8570-8578
Lowell, Andrew N; DeMars 2nd, Matthew D; Slocum, Samuel T et al. (2017) Chemoenzymatic Total Synthesis and Structural Diversification of Tylactone-Based Macrolide Antibiotics through Late-Stage Polyketide Assembly, Tailoring, and C-H Functionalization. J Am Chem Soc 139:7913-7920

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