We propose a training program designed to attract and train physicians in a two year fellowship devoted to research on the pathophysiology of injury. The goals of this training program are to nurture talented young individuals in the areas of basic research and clinical investigation, to teach them to design and perform successful research projects, and to give them a solid background in the ethics and methods of scientific research. The objective of this fellowship is to increase the focus of research on injury within the University of North Carolina (UNC) and to train individuals to become independent investigators and academic faculty with an interest in the area of trauma. Trainees will be selected from a broad group of candidates. Special efforts will be made to identify minority applicants in this and other institutions. ? ? The training program is designed to provide experience for two years of full-time effort working with a large group of talented faculty mentors. Research projects are concentrated in the areas of organ failure after injury, immunology and host resistance, and epidemiology of injury. Weekly seminars with the trainees allow them to present their material to the research community. Additionally, trainees are required to present their research at Surgery Grand Rounds, and submit abstracts for presentation to national meetings. Two intensive week-long courses, Responsible Conduct of Research and Methods in Clinical Research, are provided for trainees in the first month of the program. Trainees have the opportunity to attend graduate level courses from the broad range of didactic resources available at the UNC-CH and surrounding area universities to enhance their research experience. ? ? The Training Committee will assist the Program Director in recruitment and selection of trainees, approval of trainee's research and didactic plans, assignment of trainee to appropriate Research Training Faculty, and monitoring of program activities. The Program Evaluation Committee will provide overall evaluation of the training program and provide feedback to the Training Committee. ? ? All of the Research Training Faculty in the program are established investigators with current NIH funding or other extramural funding, and are experienced mentors of physician-scientists. The faculty have diverse interests, allowing multiple candidates to find appropriate mentors within the training program. There is a strong institutional history of multidisciplinary collaboration. A group of Clinician-Scientist mentors will provide guidance to trainees through discussion of the clinical dimensions of the research. ? ? The large number of research resources in the UNC School of Medicine and clinical resources (the Trauma Center and the North Carolina Jaycee Burn Center at UNC Hospitals) offer a rich environment for the training of young investigators who will become future academicians in the area of trauma. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
2T32GM008450-11A2
Application #
6699515
Study Section
Special Emphasis Panel (ZGM1-BRT-5 (PD))
Program Officer
Somers, Scott D
Project Start
1992-07-01
Project End
2009-06-30
Budget Start
2004-07-26
Budget End
2005-06-30
Support Year
11
Fiscal Year
2004
Total Cost
$99,905
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Knowlin, Laquanda T; Purcell, Laura; Cairns, Bruce A et al. (2018) Burn injury mortality in patients with preexisting and new onset renal disease. Am J Surg 215:1011-1015
Bartley, Colleen N; Atwell, Kenisha; Cairns, Bruce et al. (2018) Predictors of withdrawal of life support after burn injury. Burns :
Shah, Mansi; Phillips, Michael R; Quintana, Megan et al. (2018) Echocardiography allows for analysis of pulmonary arterial flow in mice with congenital diaphragmatic hernia. J Surg Res 221:35-42
Gallaher, Jared R; Banda, Wone; Lachiewicz, Anne M et al. (2018) Colonization with Multidrug-Resistant Enterobacteriaceae is Associated with Increased Mortality Following Burn Injury in Sub-Saharan Africa. World J Surg 42:3089-3096
Knowlin, Laquanda; Strassle, Paula D; Williams, Felicia N et al. (2018) Burn injury outcomes in patients with pre-existing diabetic mellitus: Risk of hospital-acquired infections and inpatient mortality. Burns 44:272-279
Atwell, Kenisha; Bartley, Colleen; Cairns, Bruce et al. (2018) Incidence of self-inflicted burn injury in patients with Major Psychiatric Illness. Burns :
Lachiewicz, Anne M; Hauck, Christopher G; Weber, David J et al. (2017) Bacterial Infections After Burn Injuries: Impact of Multidrug Resistance. Clin Infect Dis 65:2130-2136
Knowlin, Laquanda T; Stanford, Lindsay B; Cairns, Bruce A et al. (2017) The effect of preexisting respiratory co-morbidities on burn outcomes. Burns 43:366-373
Phillips, Michael R; Moore, Scott M; Shah, Mansi et al. (2017) A method for evaluating the murine pulmonary vasculature using micro-computed tomography. J Surg Res 207:115-122
Mendoza, April E; Wybourn, Christopher A; Charles, Anthony G et al. (2017) Routine computed tomography after recent operative exploration for penetrating trauma: What injuries do we miss? J Trauma Acute Care Surg 83:575-578

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