Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
2T32GM008572-06
Application #
6080240
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Flicker, Paula F
Project Start
1995-07-01
Project End
2005-06-30
Budget Start
2000-07-01
Budget End
2001-06-30
Support Year
6
Fiscal Year
2000
Total Cost
$234,761
Indirect Cost
Name
Albert Einstein College of Medicine
Department
Physiology
Type
Schools of Medicine
DUNS #
009095365
City
Bronx
State
NY
Country
United States
Zip Code
10461
Nicholas, Matthew P; Berger, Florian; Rao, Lu et al. (2015) Cytoplasmic dynein regulates its attachment to microtubules via nucleotide state-switched mechanosensing at multiple AAA domains. Proc Natl Acad Sci U S A 112:6371-6
Hayden, Eric Y; Kaur, Prerna; Williams, Thomas L et al. (2015) Heme Stabilization of ?-Synuclein Oligomers during Amyloid Fibril Formation. Biochemistry 54:4599-610
Nicholas, Matthew P; Rao, Lu; Gennerich, Arne (2014) An improved optical tweezers assay for measuring the force generation of single kinesin molecules. Methods Mol Biol 1136:171-246
Nicholas, Matthew P; Rao, Lu; Gennerich, Arne (2014) Covalent immobilization of microtubules on glass surfaces for molecular motor force measurements and other single-molecule assays. Methods Mol Biol 1136:137-69
Stewart, Alex; Harrison, Joseph S; Regula, Lauren K et al. (2013) Side chain requirements for affinity and specificity in D5, an HIV-1 antibody derived from the VH1-69 germline segment. BMC Biochem 14:9
Harrison, Joseph S; Higgins, Chelsea D; O'Meara, Matthew J et al. (2013) Role of electrostatic repulsion in controlling pH-dependent conformational changes of viral fusion proteins. Structure 21:1085-96
Koellhoffer, Jayne F; Malashkevich, Vladimir N; Harrison, Joseph S et al. (2012) Crystal structure of the Marburg virus GP2 core domain in its postfusion conformation. Biochemistry 51:7665-75
Fairman, James W; Dautin, Nathalie; Wojtowicz, Damian et al. (2012) Crystal structures of the outer membrane domain of intimin and invasin from enterohemorrhagic E. coli and enteropathogenic Y. pseudotuberculosis. Structure 20:1233-43
Capece, Luciana; Lewis-Ballester, Ariel; Yeh, Syun-Ru et al. (2012) Complete reaction mechanism of indoleamine 2,3-dioxygenase as revealed by QM/MM simulations. J Phys Chem B 116:1401-13
Harrison, Joseph S; Koellhoffer, Jayne F; Chandran, Kartik et al. (2012) Marburg virus glycoprotein GP2: pH-dependent stability of the ectodomain ?-helical bundle. Biochemistry 51:2515-25

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