The objective of this proposal is to establish a new and unique graduate training opportunity at Ohio State University (OSU), the Cellular, Molecular and Biochemical Sciences Program (CMBP). This program will draw faculty and trainees from five related molecular life sciences graduate programs: Biophysics, Microbiology, Molecular Cellular and Developmental Biology, Molecular Genetics, and the Ohio State Biochemistry Program. While these programs are very successful in training students in particular disciplines, they have not focused on providing additional coordinated interdisciplinary training opportunities as historical precedents make introduction of changes in curriculum or addition of new training modules somewhat difficult. The goal of the CMBP is to create new opportunities for student training by introducing career-advancing components. Starting with orientation week activities where students are assigned a faculty and peer mentor, and continuing with monthly research meetings, annual symposia, career workshops, ethics training, CMBP-specific courses, optional internship programs, annual evaluations, and career monitoring, CMBP trainees will experience training not available through other programs. Special CMBP features also include the requirement for a co- advisor, who will provide expertise complementary to that of the advisor on a routine basis, and a mandatory scientific writing workshop specifically developed for this program. CMBP will be a rigorous and demanding program designed to attract top students to OSU, and the breadth and depth of the training provided will position CMBP graduates to make significant contributions to biomedical research in academia, government, and industry. In the past few years, significant institutional support, together with a new Arts and Sciences College structure, has facilitated interdisciplinary research and graduate training at OSU. Thus, we feel the time is right to bring these opportunities to a new level. The resources requested in this proposal would now allow us to build on existing strengths to develop a new graduate training program that spans a broad range of topics and activities in the cellular, biochemical and molecular sciences. The unique combination of opportunities offered through the CMBP will also increase recruitment and retention of the very best graduate students, in particular from underrepresented minorities (URM), thereby building upon recent successes in similar undergraduate recruitment activities at OSU. Matching institutional support towards our goal of having one quarter of new fellowships awarded to URM students each year has been secured.
We seek to establish a new and unique graduate training opportunity at Ohio State University (OSU), the Cellular, Molecular and Biochemical Sciences Program (CMBP). This program will involve 35 faculty trainers from five related molecular life sciences graduate programs who represent the highest standards of excellence at OSU. The goal of the CMBP is to create new opportunities for student training by introducing career- advancing components, and the breadth and depth of the training provided will position CMBP graduates to make significant contributions to biomedical research in academia, government, and industry.
|Suggs, Brittany Z; Latham, Aislinn L; Dawes, Adriana T et al. (2018) FACT complex gene duplicates exhibit redundant and non-redundant functions in C. elegans. Dev Biol 444:71-82|
|Coursey, Tami; Milutinovic, Milica; Regedanz, Elizabeth et al. (2018) Arabidopsis Histone Reader EMSY-LIKE 1 Binds H3K36 and Suppresses Geminivirus Infection. J Virol 92:|
|Sherwood, Anna V; Frandsen, Jane K; Grundy, Frank J et al. (2018) New tRNA contacts facilitate ligand binding in a Mycobacterium smegmatis T box riboswitch. Proc Natl Acad Sci U S A 115:3894-3899|
|Coursey, Tami; Regedanz, Elizabeth; Bisaro, David M (2018) Arabidopsis RNA Polymerase V Mediates Enhanced Compaction and Silencing of Geminivirus and Transposon Chromatin during Host Recovery from Infection. J Virol 92:|
|Gibbs, Michelle R; Fredrick, Kurt (2018) Roles of elusive translational GTPases come to light and inform on the process of ribosome biogenesis in bacteria. Mol Microbiol 107:445-454|
|Wu, Jikang; Sabag-Daigle, Anice; Borton, Mikayla A et al. (2018) Salmonella-Mediated Inflammation Eliminates Competitors for Fructose-Asparagine in the Gut. Infect Immun 86:|
|Aten, Sydney; Hansen, Katelin F; Snider, Kaitlin et al. (2018) miR-132 couples the circadian clock to daily rhythms of neuronal plasticity and cognition. Learn Mem 25:214-229|
|Mohler, Kyle; Mann, Rebecca; Kyle, Amanda et al. (2018) Aminoacyl-tRNA quality control is required for efficient activation of the TOR pathway regulator Gln3p. RNA Biol 15:594-603|
|Tollerson 2nd, Rodney; Witzky, Anne; Ibba, Michael (2018) Elongation factor P is required to maintain proteome homeostasis at high growth rate. Proc Natl Acad Sci U S A 115:11072-11077|
|Long, Nicholas E; Sullivan, Brandon J; Ding, Haiming et al. (2018) Linker engineering in anti-TAG-72 antibody fragments optimizes biophysical properties, serum half-life, and high-specificity tumor imaging. J Biol Chem 293:9030-9040|
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