This proposal will establish a Molecular Biophysics Training Program (MBTP) at The Ohio State University. OSU has a strong group of researchers and attracts a strong student pool in molecular biophysics, but graduatetrainingandresearchisfragmentedoverseveralgraduateprograms,departments,andcolleges.The MBTPwillbringtheseentitiestogetherandcreateanintegratedtrainingexperience,inwhichstudentsfrom three differentgraduateprograms(Biophysics,OhioStateBiochemistryProgram,andtheBiologicalDivisionof Chemistry)andmanydifferentundergraduatebackgroundslearnfromeachotherandfromabroadspectrum of mentors. As a result of MBTP, all trainees will obtain core training for breadth in macromolecular and physicalbiochemistry,inthefundamentalsofbiophysics,andintheresponsibleconductofresearchtoensure thattheycancommunicateequallywellabouttoday?smostchallengingbiomedicalproblemsandaboutthe modern quantitative and molecular methods to address these, while being responsible citizens and researchers. A broad spectrum of elective courses will ensure that students have enough depth to be successful in their research projects. The envisioned training combines the best the contributing graduate programshavetooffertoprovideabetterandmorecoherenttrainingexperienceinmolecularbiophysicsthan any of the three contributing programs offer by themselves. A monthly workshop series and a yearly symposium provide cohesion to the program and incorporate unique training opportunities such as alumni presentations on nonacademic job choices, continuous engagement with ethics training, and discussion of best practices in graduate training. The resources invested into the program by NIH and matched by the institution will allow us to recruit and retain the strongest interdisciplinary students with greater inclusion of underrepresentedgroups. Guidingprinciplesofexcellence,collaborationandinterdisciplinarity,anddiversity andinclusionareusedtobuildanorganizedplanforthebesttraining,researchandcareerdevelopmentfor studentsofmolecularbiophysics.

Public Health Relevance

WeproposeestablishmentofaMolecularBiophysicsTrainingProgram(MBTP)thatleveragestheresearch andtrainingexperienceof31facultyTrainersinfourcollegesandtendepartmentstocreateauniquetraining experience at the crossroads of the quantitative, molecular, and biomedical sciences. Students from three differentgraduateprogramsandmanydifferentbackgroundswillhavetheopportunitytointeractwithandlearn fromeachotherandfromthemanyexperiencedTrainers. Thistrainingwillpreparegraduatestoaddressthe biomedicalchallengesofthetwentyfirstcenturywithtrulycollaborativeandcomprehensiveapproachesthat addresspressingneedsincareerdevelopmentandinclusionofdiversegroups.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM118291-02
Application #
9488515
Study Section
NIGMS Initial Review Group (TWD)
Program Officer
Flicker, Paula F
Project Start
2017-07-01
Project End
2022-06-30
Budget Start
2018-07-01
Budget End
2019-06-30
Support Year
2
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Ohio State University
Department
Physics
Type
Schools of Arts and Sciences
DUNS #
832127323
City
Columbus
State
OH
Country
United States
Zip Code
43210
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Cooper, Grace L; Huseby, Carol J; Chandler, Claire N et al. (2018) A liquid chromatography tandem mass spectroscopy approach for quantification of protein methylation stoichiometry. Anal Biochem 545:72-77