Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL007386-09
Application #
3540826
Study Section
Research Manpower Review Committee (MR)
Project Start
1978-07-01
Project End
1988-06-30
Budget Start
1986-07-01
Budget End
1987-06-30
Support Year
9
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Type
Organized Research Units
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Baldwin, R L; Stolowitz, M L; Hood, L et al. (1996) Structural changes of tumor necrosis factor alpha associated with membrane insertion and channel formation. Proc Natl Acad Sci U S A 93:1021-6
Parker, C G; Fessler, L I; Nelson, R E et al. (1995) Drosophila UDP-glucose:glycoprotein glucosyltransferase: sequence and characterization of an enzyme that distinguishes between denatured and native proteins. EMBO J 14:1294-303
Kagan, B L; Mirzabekov, T; Munoz, D et al. (1993) The role of channel formation in the mechanism of action of tumor necrosis factors. Ann N Y Acad Sci 707:317-27
Mikala, G; Bahinski, A; Yatani, A et al. (1993) Differential contribution by conserved glutamate residues to an ion-selectivity site in the L-type Ca2+ channel pore. FEBS Lett 335:265-9
Kagan, B L; Baldwin, R L; Munoz, D et al. (1992) Formation of ion-permeable channels by tumor necrosis factor-alpha. Science 255:1427-30
Bruce, C; Baldwin, R L; Lessnick, S L et al. (1990) Diphtheria toxin and its ADP-ribosyltransferase-defective homologue CRM197 possess deoxyribonuclease activity. Proc Natl Acad Sci U S A 87:2995-8
Hofmann, B; Nishanian, P; Baldwin, R L et al. (1990) HIV inhibits the early steps of lymphocyte activation, including initiation of inositol phospholipid metabolism. J Immunol 145:3699-705
Chang, M P; Baldwin, R L; Bruce, C et al. (1989) Second cytotoxic pathway of diphtheria toxin suggested by nuclease activity. Science 246:1165-8