This T32 renewal application for years 27-31 seeks continuing support for this exemplary Lung Biology and Pathobiology Training Program at The University of Illinois College of Medicine, Chicago. Our primary emphasis continues to be in the training of the next generation of creative and meritorious lung researchers at the predoctoral and postdoctoral levels. To support our goal of training in this rapidly-evolving and competitive scientific environment, we have re-vitalized the program to encompass development of careers of individuals seeking to become independent investigators as well as aspiring to research-related careers. The Program continues to have a strong focus on fostering career development and promoting essential skills such as in problem-solving skills and developing characteristics such as resilience and grit which are necessary for long- term success in any research-intensive career. Our alumni move on to successful careers in academia, industry, and related-fields. In addition to the cohort of stellar well-funded preceptors we have always had, we have selectively replenished our faculty to provide to new training opportunities. Our Training Program covers five complementary thematic areas: (1) Biology and Pathobiology of the Lung Vasculature, (2) Regenerative Mechanisms in Lung and Vascular Biology, (3) Cellular and Humoral Basis of Lung Inflammation and Injury, (4) Cell Signaling in Lung Injury, and (5) Lung and Vascular Genomics. The Program's vitality is reflected in the numbers of highly qualified applicants applying and those we must decline. We anticipate an even greater interest with the launch of new thematic areas, recruitment of exceptional faculty, and programs such as the internally funded internship program and summer undergraduate research program to attract better trainees. Therefore, we are requesting 7 predoctoral (as opposed to 6 PhD trainees currently) while maintaining 6 postdoctoral training positions. The Program is designed to provide mentoring by a primary preceptor, however co-mentorship is encouraged. Trainees formulate Individual Development Plans with their mentor(s) and their progress is carefully monitored throughout based on various systems and checks and balances in place. Thus, we are poised with renewed vigor to train a select group of individuals in lung-related research and important intersecting disciplines for careers in academia, research institutions, biopharmaceutical industry, and other burgeoning areas.

Public Health Relevance

This training grant application focused on lung biology and pathobiology requests continuing support for 7 predoctoral and 6 postdoctoral trainees. The Training Program is grounded in 5 inter-related thematic areas of research training: (1) Biology and Pathobiology of Lung Vasculature, (2) Regenerative Mechanisms in Lung and Vascular Biology, (3) Cellular and Humoral Bases of Lung Inflammation and Injury, (4) Cell Signaling Mechanisms in Lung Injury, and (5) Lung and Vascular Genomics. We are well positioned to continue to train a highly-qualitied group of young scientists, providing a range of skills needed in a rapidly-evolving and increasingly competitive scientific environment that can be applied in careers in both academic research and alternative pathways.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
2T32HL007829-27
Application #
9855323
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Kalantari, Roya
Project Start
1995-07-01
Project End
2025-07-31
Budget Start
2020-08-01
Budget End
2021-07-31
Support Year
27
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Pharmacology
Type
Schools of Medicine
DUNS #
098987217
City
Chicago
State
IL
Country
United States
Zip Code
60612
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