The Brown CardioPulmonary Training Program has as its overall objective the training of physicians and scientists who will become independent investigators in the molecular basis and pathobiology of cardiovascular and pulmonary diseases and the outcomes of prevention and treatment of these diseases. This will be accomplished by a rigorous program of didactic training and mentored research experience in a collaborative, multidisciplinary setting with career development training. Four postdoctoral trainees with an MD, PhD, or MD/PhD degree will be accepted per year into a 3- year research training program. Thirty-three experienced and well-funded faculty trainers plus seven promising junior faculty trainers from 11 academic departments have developed a Training Program that utilizes resources from 7 Brown teaching hospitals plus Brown University. The Training Program aims to bridge gaps between bio-medical, behavioral and public health disciplines to advance knowledge regarding how best to reduce disease burden among patients with diseases that affect the cardiovascular system and lungs. This will be accomplished by training in Molecular Pathobiology of Cardiovascular and Pulmonary Diseases or in Health Services/Outcomes. This Training Program is uniquely positioned to train individuals in research related to diseases that involve these systems, such as aging. Having trainees looking at these problems from both bench to bedside and bedside to practice aspects can lead to new insights, lines of synergistic research and advances in science using both molecular methods and epidemiologic, clinical trials, and health services investigations.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL094300-03
Application #
7905834
Study Section
Special Emphasis Panel (ZHL1-CSR-R (O2))
Program Officer
Commarato, Michael
Project Start
2008-09-01
Project End
2013-08-31
Budget Start
2010-09-01
Budget End
2011-08-31
Support Year
3
Fiscal Year
2010
Total Cost
$549,680
Indirect Cost
Name
Rhode Island Hospital
Department
Type
DUNS #
075710996
City
Providence
State
RI
Country
United States
Zip Code
02903
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Vang, Alexander; Clements, Richard T; Chichger, Havovi et al. (2017) Effect of ?7 nicotinic acetylcholine receptor activation on cardiac fibroblasts: a mechanism underlying RV fibrosis associated with cigarette smoke exposure. Am J Physiol Lung Cell Mol Physiol 312:L748-L759
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Kim, Tae Yun; Terentyeva, Radmila; Roder, Karim H F et al. (2017) SK channel enhancers attenuate Ca2+-dependent arrhythmia in hypertrophic hearts by regulating mito-ROS-dependent oxidation and activity of RyR. Cardiovasc Res 113:343-353
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