The Brown Respiratory Research Training Program has as its overall objective the training of physicians and scientists who will become independent investigators in the pathobiology of respiratory diseases and in the health services, outcomes, and epidemiology of these diseases. This will be accomplished by a rigorous program of didactic and career development training and mentored research experience in a collaborative, multidisciplinary setting. Two graduate students will be accepted per year into a 2-year research training program focused on Pathogenesis of Respiratory Diseases, with an emphasis on Infections and Immunity. In addition, two postdoctoral trainees with an MD, PhD, or MD/PhD degree will be accepted per year into a 2-year research training program focused on either Pathogenesis of Respiratory Diseases or Health Services, Outcomes, and Epidemiology of Respiratory Diseases. In the first grant year there will be a total of 4 trainees, in subsequent years there will be 8 trainees total. Twenty six experienced and well-funded faculty trainers plus nine promising junior faculty trainers from 11 academic departments have developed a Training Program that utilizes resources from 3 Brown teaching hospitals plus Brown Biology and Clinical Departments and the Brown School of Public Health. The Brown Respiratory Research Training Program aims to bridge gaps between biomedical, behavioral and public health disciplines to advance knowledge regarding how best to reduce disease burden among patients with diseases that affect the respiratory system. The Brown Respiratory Research Training Program is uniquely positioned to train individuals in research related to respiratory diseases, and takes special advantage of resources in training in Infection and Immunity. Having trainees looking at these problems from both bench to bedside and bedside to practice aspects can lead to new insights, lines of synergistic research, and advances in science using molecular methods and epidemiologic, clinical trials, and health services investigations.

Public Health Relevance

The overall goal of the Brown Respiratory Research Training Program is to develop MD and PhD scientists whose research will improve understanding of the causes of respiratory diseases and improve the treatment and outcomes of these disorders. The program includes both pre-doctoral and post-doctoral training, including coursework, career development training, and mentored research.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Special Emphasis Panel (NITM (OA))
Program Officer
Colombini-Hatch, Sandra
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Brown University
Internal Medicine/Medicine
Schools of Medicine
United States
Zip Code
Biron, Bethany M; Chung, Chun-Shiang; Chen, Yaping et al. (2018) PAD4 Deficiency Leads to Decreased Organ Dysfunction and Improved Survival in a Dual Insult Model of Hemorrhagic Shock and Sepsis. J Immunol 200:1817-1828
Lee, Kayla M; Morris-Love, Jenna; Cabral, Damien J et al. (2018) Coinfection With Influenza A Virus and Klebsiella oxytoca: An Underrecognized Impact on Host Resistance and Tolerance to Pulmonary Infections. Front Immunol 9:2377
Crane, Meredith J; Lee, Kayla M; FitzGerald, Ethan S et al. (2018) Surviving Deadly Lung Infections: Innate Host Tolerance Mechanisms in the Pulmonary System. Front Immunol 9:1421