The Multidisciplinary Pulmonary Research Training Program in the Lung Institute at Cedars-Sinai Medical Center (CSMC) is focused on developing young biomedical researchers into independent academic investigators dedicated to studies in respiratory diseases. CSMC has academically been in a growth phase with a large influx of investigators all with well-recognized research programs in respiratory research. Importantly, these investigators are highly interactive and dedicated to training the future generation of respiratory researchers and bring an established track record of training to the Lung Institute at CSMC. This new training program will be directed by Paul Noble, MD who is the Chair of the Department of Medicine and Director of the Lung Institute at CSMC. An Executive Committee comprised of William Parks, PhD (Scientific Director of the Lung Institute) and Peter Chen, MD (Director, Division of Pulmonary and Critical Care Medicine) will support Dr. Noble in the administration of the training program. Four positions will be available for MD, MD/PhD, and PhD scientists to train in basic and translational respiratory research. Trainees will have a structured 3-year curriculum that is primarily based in laboratory research and complemented with didactic courses, seminars, and workshops. The coursework will provide instruction on topics such as research integrity and bioethics, biostatistics, and grantsmanship. Trainees will have a primary mentor (often coupled with a co- mentor) to guide their research training in 5 areas: 1) Inflammation and host defense; 2) Remodeling and fibrosis; 3) Immunology; 4) Regeneration; and 5) Cancer. A Mentoring Committee will also be created to oversee the overall training progression and career development of the trainee during the training period and beyond. Upon completion of the training program, the trainee will be required to demonstrate research productivity (i.e., publications), growth toward independence in developing research questions and implementing their studies, and grantsmanship skills with successful submissions for research funding.

Public Health Relevance

Respiratory diseases is the third leading cause of death and a major contributor to morbidity. Therefore, maintaining a biomedical workforce in pulmonary research is necessary in order to discover mechanisms of disease and novel therapies. The Multidisciplinary Pulmonary Research Training Program provides a structured environment for early career investigators to train with mentors established in the field of respiratory research.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL134637-05
Application #
10115099
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Kalantari, Roya
Project Start
2017-02-01
Project End
2022-01-31
Budget Start
2021-02-01
Budget End
2022-01-31
Support Year
5
Fiscal Year
2021
Total Cost
Indirect Cost
Name
Cedars-Sinai Medical Center
Department
Type
DUNS #
075307785
City
Los Angeles
State
CA
Country
United States
Zip Code
90048
Sims, Jessica D; Taguiam, Jan Michael; Alonso-Valenteen, Felix et al. (2018) Resistance to receptor-blocking therapies primes tumors as targets for HER3-homing nanobiologics. J Control Release 271:127-138
Xie, Ting; Wang, Yizhou; Deng, Nan et al. (2018) Single-Cell Deconvolution of Fibroblast Heterogeneity in Mouse Pulmonary Fibrosis. Cell Rep 22:3625-3640
Song, Isabelle Jingyi; Yang, Yoon Mee; Inokuchi-Shimizu, Sayaka et al. (2018) The contribution of toll-like receptor signaling to the development of liver fibrosis and cancer in hepatocyte-specific TAK1-deleted mice. Int J Cancer 142:81-91
Yang, Yoon Mee; Fukui, Masato; Wang, Zhijun et al. (2018) Interventional Potential of Recombinant Feline Hepatocyte Growth Factor in a Mouse Model of Non-alcoholic Steatohepatitis. Front Endocrinol (Lausanne) 9:378
Yao, Changfu; Carraro, Gianni; Konda, Bindu et al. (2017) Sin3a regulates epithelial progenitor cell fate during lung development. Development 144:2618-2628