The primary goal of this grant proposal is to promote interdisciplinary research in neurobehavioral development at the postdoctoral level. We will target trainees who have received a Ph.D. in Child Psychology, Neuroscience or Developmental Neuroscience-related disciplines (e.g., molecular or developmental biology), as well as M.D.'s in various Pediatric disciplines, such as Neonatology, Pediatric Neurology and Child Psychiatry. The motivation behind this proposal is to foster the development of junior investigators who can integrate research and theory in human behavioral development with explication of underlying neural circuitry and neurodevelopmental processes. A long-range goal is to create a discipline we have come to call """"""""neurobehavioral development."""""""" Clearly, knowledge of the neurobiological mechanisms underlying behavioral development would benefit those interested in a range of behavioral phenomena, and vice versa. To date there are relatively few developmental researchers who work at this interdisciplinary boundary in either basic or clinical domains. Consequently, there is a tremendous need to foster this integration among principal investigators and to support the interdisciplinary training of students. This is the mission of the Center for Neurobehavioral Development (CNBD) at the University of Minnesota, which will be home to this training grant. The CNBD accomplishes this mission by providing research space, educational colloquia and classes co-listed in multiple relevant departments, and by having a core faculty consisting of developmental, cognitive, behavioral, and basic neuroscientists working at multiple tiers of investigation in the human and in animal models. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Institutional National Research Service Award (T32)
Project #
5T32MH073129-03
Application #
7115341
Study Section
Special Emphasis Panel (ZMH1-CRB-O (01))
Program Officer
Desmond, Nancy L
Project Start
2004-09-29
Project End
2009-07-31
Budget Start
2006-08-01
Budget End
2007-07-31
Support Year
3
Fiscal Year
2006
Total Cost
$413,176
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Pediatrics
Type
Schools of Medicine
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Herzberg, Max P; Hodel, Amanda S; Cowell, Raquel A et al. (2018) Risk taking, decision-making, and brain volume in youth adopted internationally from institutional care. Neuropsychologia 119:262-270
Jabès, Adeline; Thomas, Kathleen M; Langworthy, Sara et al. (2015) Functional and Anatomic Consequences of Diabetic Pregnancy on Memory in Ten-Year-Old Children. J Dev Behav Pediatr 36:529-35
Hodel, Amanda S; Hunt, Ruskin H; Cowell, Raquel A et al. (2015) Duration of early adversity and structural brain development in post-institutionalized adolescents. Neuroimage 105:112-9
Cohen-Gilbert, Julia E; Thomas, Kathleen M (2013) Inhibitory control during emotional distraction across adolescence and early adulthood. Child Dev 84:1954-66
Guler, O Evren; Thomas, Kathleen M (2013) Developmental differences in the neural correlates of relational encoding and recall in children: an event-related fMRI study. Dev Cogn Neurosci 3:106-16
Meitzen, John; Grove, Danielle D; Mermelstein, Paul G (2012) The organizational and aromatization hypotheses apply to rapid, nonclassical hormone action: neonatal masculinization eliminates rapid estradiol action in female hippocampal neurons. Endocrinology 153:4616-21
Cullen, Kathryn; Guimaraes, Angela; Wozniak, Jeffrey et al. (2011) Trajectories of social withdrawal and cognitive decline in the schizophrenia prodrome. Clin Schizophr Relat Psychoses 4:229-38
Grove-Strawser, D; Boulware, M I; Mermelstein, P G (2010) Membrane estrogen receptors activate the metabotropic glutamate receptors mGluR5 and mGluR3 to bidirectionally regulate CREB phosphorylation in female rat striatal neurons. Neuroscience 170:1045-55
Tran, Phu V; Georgieff, Michael K; Engeland, William C (2010) Sodium depletion increases sympathetic neurite outgrowth and expression of a novel TMEM35 gene-derived protein (TUF1) in the rat adrenal zona glomerulosa. Endocrinology 151:4852-60
Cullen, Kathryn R; Klimes-Dougan, Bonnie; Muetzel, Ryan et al. (2010) Altered white matter microstructure in adolescents with major depression: a preliminary study. J Am Acad Child Adolesc Psychiatry 49:173-83.e1

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